Endocannabinoid system: chemical characteristics and biological activity

B Rezende, AKN Alencar, GF de Bem… - Pharmaceuticals, 2023 - mdpi.com
The endocannabinoid system (eCB) has been studied to identify the molecular structures
present in Cannabis sativa. eCB consists of cannabinoid receptors, endogenous ligands …

Synthetic pathways to non-psychotropic phytocannabinoids as promising molecules to develop novel antibiotics: A review

S Alfei, GC Schito, AM Schito - Pharmaceutics, 2023 - mdpi.com
Due to the rapid emergence of multi drug resistant (MDR) pathogens against which current
antibiotics are no longer functioning, severe infections are becoming practically untreatable …

Impact of the cannabinoid system in Alzheimer's Disease

S Li, Y Huang, L Yu, X Ji, J Wu - Current Neuropharmacology, 2023 - benthamdirect.com
Cannabinoids are compounds isolated from cannabis and are also widely present in both
nervous and immune systems of animals. In recent years, with in-depth research on …

[HTML][HTML] The endocannabinoid system: A new frontier in addressing psychosomatic challenges

LE Torres-Mondragón, LC León-Pimentel… - Journal of Clinical …, 2024 - accscience.com
Psychosomatic disorders (PSD), alternatively referred to as psychophysiologic disorders,
are characterized by hypothalamic-pituitary-adrenal (HPA) axis activation, posing a …

The progress of small molecules against cannabinoid 2 receptor (CB2R)

Q Zhang, Y Zhao, J Wu, W Zhong, W Huang, Y Pan - Bioorganic Chemistry, 2024 - Elsevier
The two subtypes of cannabinoid receptors (CBR), namely CB 1 R and CB 2 R, belong to
the G protein-coupled receptor (GPCR) superfamily and are confirmed as potential …

Indicações da Cannabis sativa na terapêutica veterinária–revisão sistemática

F dos Santos Correia… - …, 2024 - ojs.observatoriolatinoamericano …
A Cannabis sativa L. tem sido usada ao longo da história por suas propriedades medicinais
e, recentemente, seu uso na medicina veterinária tem ganhado mais atenção. Estudos …

[PDF][PDF] The Interplay between 2-Arachidonoylglycerol and Anandamide Amidohydrolase in Neuropathy

I Ibrahim, J Ayariga, J Xu, B Robertson, O Ajayi - 2024 - preprints.org
The endocannabinoid system (ECS) is a complex neuromodulatory network in the human
body that have enormous impact in develo** the central nervous system, as well as …

Citrobacter rodentium infection at the gut–brain axis interface

FH Martins, S Cuesta - Current opinion in microbiology, 2021 - Elsevier
Highlights•Gut–brain crosstalk regulates pathogen colonization and host behavioral
responses.•Citrobacter rodentium senses gut neurochemical signals to regulate …

Endocannabinoid levels in peripheral blood mononuclear cells of multiple sclerosis patients treated with dimethyl fumarate

A Sánchez-Sanz, M Posada-Ayala, J Sabín-Muñoz… - Scientific Reports, 2022 - nature.com
The endocannabinoid system (ECS), a signalling network with immunomodulatory
properties, is a potential therapeutic target in multiple sclerosis (MS). Dimethyl fumarate …

Circulating Endocannabinoids in Huntington's Disease: An Exploratory Cross-Sectional Study

P Manzke, JAS Crippa, C Marchioni… - Journal of …, 2022 - journals.sagepub.com
Huntington's disease (HD) is an inherited neurodegenerative disease characterized by
motor, cognitive and behavioral deficits. Some evidence suggests that the endocannabinoid …