Knockdown of mesenchymal stem cell‑derived exosomal LOC100129516 suppresses the symptoms of atherosclerosis via upregulation of the PPARγ/LXRα/ABCA1 …
L Sun, X He, T Zhang, Y Han… - … journal of molecular …, 2021 - spandidos-publications.com
Mesenchymal stem cell (MSC) therapy has potential applications in treating atherosclerosis
and coronary heart disease (CAD). Previous studies have demonstrated that MSCs are the …
and coronary heart disease (CAD). Previous studies have demonstrated that MSCs are the …
Gut dysbiosis and adaptive immune response in diet-induced obesity vs. systemic inflammation
J Pindjakova, C Sartini, O Lo Re, F Rappa… - Frontiers in …, 2017 - frontiersin.org
A mutual interplay exists between adaptive immune system and gut microbiota. Altered gut
microbial ecosystems are associated with the metabolic syndrome, occurring in most obese …
microbial ecosystems are associated with the metabolic syndrome, occurring in most obese …
[HTML][HTML] Small interfering RNA-induced silencing lncRNA PVT1 inhibits atherosclerosis via inactivating the MAPK/NF-κB pathway
H Du, H Zhang, R Yang, L Qiao, H Shao… - Aging (Albany NY …, 2021 - ncbi.nlm.nih.gov
Atherosclerosis (AS) is a chronic disease of the arterial wall. The role of lncRNAs in AS has
been acknowledged. This study investigated the role of lncRNA plasmacytoma variant …
been acknowledged. This study investigated the role of lncRNA plasmacytoma variant …
Rutaecarpine derivative R3 attenuates atherosclerosis via inhibiting NLRP3 inflammasome‐related inflammation and modulating cholesterol transport
J Luo, X Wang, X Jiang, C Liu, Y Li, X Han… - The FASEB …, 2020 - Wiley Online Library
Atherosclerosis is a chronic disease characterized by lipid deposition and inflammatory
response. NOD‐, LRR‐and pyrin domain‐containing protein 3 (NLRP3) inflammasome …
response. NOD‐, LRR‐and pyrin domain‐containing protein 3 (NLRP3) inflammasome …
Increased hepatic fatty acids uptake and oxidation by LRPPRC-driven oxidative phosphorylation reduces blood lipid levels
S Lei, R Sun, D Wang, M Gong, X Su, F Yi… - Frontiers in …, 2016 - frontiersin.org
Hyperlipidemia is one of the major risk factors of atherosclerosis and other cardiovascular
diseases. This study aimed to investigate the impact of leucine rich pentatricopeptide repeat …
diseases. This study aimed to investigate the impact of leucine rich pentatricopeptide repeat …
MiR-135a-5p inhibits vascular smooth muscle cells proliferation and migration by inactivating FOXO1 and JAK2 signaling pathway
D Li, Y An - Pathology-Research and Practice, 2021 - Elsevier
Background It is reportedly demonstrated that miR-135a-5p plays a critical role in cancer
cells, macrophages, and endothelia cells. However, little is known concerning the function of …
cells, macrophages, and endothelia cells. However, little is known concerning the function of …
miR-17 regulates the proliferation and apoptosis of endothelial cells in coronary heart disease via targeting insulin-like-growth factor 1
Z Chen, X Pan, Z Sheng, G Yan, L Chen… - Pathology-Research and …, 2019 - Elsevier
Coronary heart disease (CHD) is one of the main risks of death, which is mainly caused by
coronary arteries arteriosclerosis. The present study aims to investigate the potential roles of …
coronary arteries arteriosclerosis. The present study aims to investigate the potential roles of …
miR-133b downregulation reduces vulnerable plaque formation in mice with AS through inhibiting macrophage immune responses
CG Zheng, BY Chen, RH Sun, XZ Mou, F Han… - … Therapy-Nucleic Acids, 2019 - cell.com
Atherosclerosis (AS) is a chronic inflammatory disease characterized by accumulating
deposition of lipids in the arterial intima. Notably, macrophages participate centrally in the …
deposition of lipids in the arterial intima. Notably, macrophages participate centrally in the …
SORBS2 as a molecular target for atherosclerosis in patients with familial hypercholesterolemia
MM Liu, J Peng, YL Guo, CG Zhu, NQ Wu… - Journal of Translational …, 2022 - Springer
Background Familial hypercholesterolemia (FH) is a metabolic disease in which patients are
prone to develop premature atherosclerosis (AS). Sorbin and SH3 Domain Containing 2 …
prone to develop premature atherosclerosis (AS). Sorbin and SH3 Domain Containing 2 …
TRIF Regulates BIC/miR‐155 via the ERK signaling pathway to control the ox‐LDL‐Induced macrophage inflammatory response
Y Wu, J Ye, R Guo, X Liang… - Journal of Immunology …, 2018 - Wiley Online Library
Toll/IL‐1R‐domain‐containing adaptor‐inducing IFN‐β (TRIF) is an important adaptor for
TLR3‐and TLR4‐mediated inflammatory signaling pathways. Recent studies have shown …
TLR3‐and TLR4‐mediated inflammatory signaling pathways. Recent studies have shown …