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We are witnessing a notable rise in the translational use of information technology and
control systems engineering tools in clinical practice. This paper empowers the computer …

Slow convergence and low accuracy are two main drawbacks in nonlinear system
identification methods. It becomes more complicated when time delay and noises are …

Purpose We evaluated the feasibility and robustness of three methods for propofol-to-
bispectral index (BIS) post-operative intensive care sedation, a manually-adapted target …

This paper describes the design of a robust proportional-integral derivative (PID) controller
for propofol infusion in children and presents the results of clinical evaluation of this closed …

Fractional calculus has become an increasingly popular tool for modeling the complex
behaviors of physical systems from diverse domains. One of the key issues to apply …

In today's healthcare paradigm, optimal sedation during anesthesia plays an important role
both in patient welfare and in the socio-economic context. For the closed-loop control of …

In this paper is presented a brief state of art regarding the multivariable formulation for
controlling the depth of anaesthesia by means of two intravenously administrated drugs, ie …

System identification through fractional models is proposed for modeling thermal transfers in
the lungs. In general, during open-heart surgery, an extracorporeal circulation is carried out …

Although the measurement of dielectric properties of the skin is a long-known tool for
assessing the changes caused by nociception, the frequency modulated response has not …