Imaging and biophysical modelling of thrombogenic mechanisms in atrial fibrillation and stroke
Atrial fibrillation (AF) underlies almost one third of all ischaemic strokes, with the left atrial
appendage (LAA) identified as the primary thromboembolic source. Current stroke risk …
appendage (LAA) identified as the primary thromboembolic source. Current stroke risk …
A review of quantitative systems pharmacology models of the coagulation Cascade: opportunities for improved usability
D Chung, S Bakshi, PH van der Graaf - Pharmaceutics, 2023 - mdpi.com
Despite the numerous therapeutic options to treat bleeding or thrombosis, a comprehensive
quantitative mechanistic understanding of the effects of these and potential novel therapies …
quantitative mechanistic understanding of the effects of these and potential novel therapies …
Modelling and simulations of the SEIR and Blood Coagulation systems using Atangana-Baleanu-Caputo derivative
In this work, we investigate the SEIR and Blood Coagulation systems using a specific type of
fractional derivative. SEIR epidemic model which outlines the close communication of …
fractional derivative. SEIR epidemic model which outlines the close communication of …
Novel mathematical modelling of platelet-poor plasma arising in a blood coagulation system with the fractional Caputo–Fabrizio derivative
This study develops a fractional model using the Caputo–Fabrizio derivative with order α for
platelet-poor plasma arising in a blood coagulation system. The existence of solutions …
platelet-poor plasma arising in a blood coagulation system. The existence of solutions …
[HTML][HTML] Influence of vortical structures on fibrin clot formation in cerebral aneurysms: A two-dimensional computational study
Thrombosis is an important contributor to cerebral aneurysm growth and progression. A
number of sophisticated multiscale and multiphase in silico models have been developed …
number of sophisticated multiscale and multiphase in silico models have been developed …
Combining mathematical modeling and deep learning to make rapid and explainable predictions of the patient-specific response to anticoagulant therapy under …
Anticoagulant drugs are commonly prescribed to prevent hypercoagulable states in patients
with venous thromboembolism. The choice of the most efficient anticoagulant and the …
with venous thromboembolism. The choice of the most efficient anticoagulant and the …
A mathematical model of blood loss during renal resection
In 2021, approximately 51% of patients diagnosed with kidney tumors underwent surgical
resections. One possible way to reduce complications from surgery is to minimise the …
resections. One possible way to reduce complications from surgery is to minimise the …
Thrombin Generation Thresholds for Coagulation Initiation under Flow
In veins, clotting initiation displays a threshold response to flow intensity and injury size.
Mathematical models can provide insights into the conditions leading to clot growth initiation …
Mathematical models can provide insights into the conditions leading to clot growth initiation …
Hemodynamics Affects Factor XI/XII Anticoagulation Efficacy in Patient-Specific Left Atrial Models
Atrial fibrillation (AF) disrupts the circulation of blood through the left atrium (LA), and may
result in relative stasis in the left atrial appendage (LAA), increasing thromboembolic risk …
result in relative stasis in the left atrial appendage (LAA), increasing thromboembolic risk …
A novel interferometry-based optical sensor to study the coagulation of human plasma
A Das, KR Nair, H Ashok, T Subeesh… - Optics & Laser …, 2025 - Elsevier
We propose and demonstrate a Twin-interferometry (TIM) based optical approach for
studying and exploring anisotropy and directional dependent coagulation kinetics in human …
studying and exploring anisotropy and directional dependent coagulation kinetics in human …