The collagen suprafamily: from biosynthesis to advanced biomaterial development
Collagen is the oldest and most abundant extracellular matrix protein that has found many
applications in food, cosmetic, pharmaceutical, and biomedical industries. First, an overview …
applications in food, cosmetic, pharmaceutical, and biomedical industries. First, an overview …
[HTML][HTML] Extracellular matrix-derived materials for tissue engineering and regenerative medicine: a journey from isolation to characterization and application
Biomaterial choice is an essential step during the development tissue engineering and
regenerative medicine (TERM) applications. The selected biomaterial must present …
regenerative medicine (TERM) applications. The selected biomaterial must present …
Scaffold-free cell-based tissue engineering therapies: advances, shortfalls and forecast
Cell-based scaffold-free therapies seek to develop in vitro organotypic three-dimensional
(3D) tissue-like surrogates, capitalising upon the inherent capacity of cells to create tissues …
(3D) tissue-like surrogates, capitalising upon the inherent capacity of cells to create tissues …
Cell-derived extracellular matrix for tissue engineering and regenerative medicine
Cell-derived extracellular matrices (CD-ECMs) captured increasing attention since the first
studies in the 1980s. The biological resemblance of CD-ECMs to their in vivo counterparts …
studies in the 1980s. The biological resemblance of CD-ECMs to their in vivo counterparts …
Dermal fibroblasts have different extracellular matrix profiles induced by TGF-β, PDGF and IL-6 in a model for skin fibrosis
Different stimulants might induce different extracellular matrix profiles. It is essential to gain
an understanding and quantification of these changes to allow for focused anti-fibrotic drug …
an understanding and quantification of these changes to allow for focused anti-fibrotic drug …
Mechanical properties of cell sheets and spheroids: the link between single cells and complex tissues
YM Efremov, IM Zurina, VS Presniakova… - Biophysical …, 2021 - Springer
Cell aggregates, including sheets and spheroids, represent a simple yet powerful model
system to study both biochemical and biophysical intercellular interactions. However, it is …
system to study both biochemical and biophysical intercellular interactions. However, it is …
[HTML][HTML] It is time to crowd your cell culture media–physicochemical considerations with biological consequences
D Tsiapalis, DI Zeugolis - Biomaterials, 2021 - Elsevier
In vivo, the interior and exterior of cells is populated by various macromolecules that create
an extremely crowded milieu. Yet again, in vitro eukaryotic cell culture is conducted in dilute …
an extremely crowded milieu. Yet again, in vitro eukaryotic cell culture is conducted in dilute …
An experimental toolbox for characterization of mammalian collagen type I in biological specimens
Collagen type I is the most abundant extracellular matrix protein, and collagen type I
supramolecular assemblies (eg, tissue grafts, biomaterials and cell-assembled systems) are …
supramolecular assemblies (eg, tissue grafts, biomaterials and cell-assembled systems) are …
Bioactive decellularized extracellular matrix derived from 3D stem cell spheroids under macromolecular crowding serves as a scaffold for tissue engineering
CE Chiang, YQ Fang, CT Ho… - Advanced …, 2021 - Wiley Online Library
Scaffolds for tissue engineering aim to mimic the native extracellular matrix (ECM) that
provides physical support and biochemical signals to modulate multiple cell behaviors …
provides physical support and biochemical signals to modulate multiple cell behaviors …
Extracellular matrix deposition of bone marrow stroma enhanced by macromolecular crowding
Decellularized extracellular matrices (ECM) from in vitro cell cultures can serve as in vivo-
like matrix scaffolds for modulating cell-ECM interactions. Macromolecular crowding (MMC) …
like matrix scaffolds for modulating cell-ECM interactions. Macromolecular crowding (MMC) …