PPARγ/PGC1α signaling as a potential therapeutic target for mitochondrial biogenesis in neurodegenerative disorders
S Jamwal, JK Blackburn, JD Elsworth - Pharmacology & Therapeutics, 2021 - Elsevier
Neurodegenerative diseases represent some of the most devastating neurological
disorders, characterized by progressive loss of the structure and function of neurons. Current …
disorders, characterized by progressive loss of the structure and function of neurons. Current …
Parsing the role of PPARs in macrophage processes
Cells are richly equipped with nuclear receptors, which act as ligand-regulated transcription
factors. Peroxisome proliferator activated receptors (PPARs), members of the nuclear …
factors. Peroxisome proliferator activated receptors (PPARs), members of the nuclear …
Lipid metabolism and plasma metabolomics of juvenile largemouth bass Micropterus salmoides were affected by dietary oxidized fish oil
S **e, P Yin, L Tian, Y Liu, J Niu - Aquaculture, 2020 - Elsevier
During the storage, fish oil is susceptible to peroxidation to form toxic lipid derivatives,
dietary intake of oxidized fish oil would induce oxidative stress and inflammation in animals …
dietary intake of oxidized fish oil would induce oxidative stress and inflammation in animals …
Phytochemicals as modulators of paraoxonase-1 in health and diseases
Chronic diseases such as cardiovascular disease (CVD), atherosclerosis, chronic liver
disease, and neurodegenerative diseases are major causes of mortality. These diseases …
disease, and neurodegenerative diseases are major causes of mortality. These diseases …
The role of high-density lipoprotein cholesterol, apolipoprotein A and paraoxonase-1 in the pathophysiology of neuroprogressive disorders
Lowered high-density lipoprotein (HDL) cholesterol has been reported in major depressive
disorder, bipolar disorder, first episode of psychosis, and schizophrenia. HDL, its major …
disorder, bipolar disorder, first episode of psychosis, and schizophrenia. HDL, its major …
Mitigating multiple stresses in Pangasianodon hypophthalmus with a novel dietary mixture of selenium nanoparticles and Omega-3-fatty acid
Abstract Effects of a novel dietary mixture of selenium nanoparticles (Se-NPs) and omega-3-
fatty acids ie, Eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) on mitigating …
fatty acids ie, Eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) on mitigating …
The relationship between cancer and paraoxonase 1
IM Medina-Díaz, N Ponce-Ruíz, AE Rojas-García… - Antioxidants, 2022 - mdpi.com
Extensive research has been carried out to understand and elucidate the mechanisms of
paraoxonase 1 (PON1) in the development of diseases including cancer, cardiovascular …
paraoxonase 1 (PON1) in the development of diseases including cancer, cardiovascular …
Modulatory effect of lifestyle-related, environmental and genetic factors on paraoxonase-1 activity: a review
Paraoxonase-1 (PON1) is a calcium-dependent, HDL-bound serum hydrolase active toward
a wide variety of substrates. PON1 displays three types of activities, among which lactonase …
a wide variety of substrates. PON1 displays three types of activities, among which lactonase …
A review of paraoxonase 1 properties and diagnostic applications
M Kulka - Polish journal of veterinary sciences, 2016 - journals.pan.pl
Abstract Paraoxonase 1 (PON1) is an arylesterase associated with serum high density
lipoprotein particles. Its name is derived from hydrolyzing one of several organophosphate …
lipoprotein particles. Its name is derived from hydrolyzing one of several organophosphate …
Combined western diet and bisphenol A exposure induces an oxidative stress-based paraoxonase 1 response in larval zebrafish
R van den Boom, L Vergauwen, N Koedijk… - … and Physiology Part C …, 2023 - Elsevier
Abstract Paraoxonase 1 (PON1) is an antioxidant enzyme linked to metabolic disorders by
genome-wide association studies in humans. Exposure to metabolic disrupting chemicals …
genome-wide association studies in humans. Exposure to metabolic disrupting chemicals …