Epigenetics has long been recognized as a significant field in biology and is defined as the
investigation of any alteration in gene expression patterns that is not attributed to changes in …

In the next 10 years, one billion people are estimated to suffer from disabling consequences
of metabolic disorders, making them the number one noncommunicable disease on a global …

Gene mutations are strongly associated with tumor progression and are well known in
cancer development. However, recently discovered epigenetic alterations have shown the …

Breast cancer is a sporadic disease with genetic and epigenetic components. Genomic
instability in breast cancer leads to mutations, copy number variations, and genetic …

Objectives: Recent evidence from the fields of microbiology and immunology, as well as a
small number of human sepsis studies, suggest that epigenetic regulation may play a central …

Biomarkers are a class of measurable and evaluable indicators with the potential to predict
disease initiation and progression. In contrast to disease-associated factors, biomarkers …

Numerous environmental factors such as diet, alcohol use, stress, and environmental
chemicals are known to elicit epigenetic changes, leading to increased rates of cancers and …

Epigenetics is mainly comprised of features that regulate genomic interactions thereby
playing a crucial role in a vast array of biological processes. Epigenetic mechanisms such …

The polygenic nature of neurological and psychiatric syndromes and the significant impact
of environmental factors on the underlying developmental, homeostatic, and neuroplastic …

The promise of drug repurposing is to accelerate the translation of knowledge to treatment of
human disease, bypassing common challenges associated with drug development to be …