The nature of consciousness, the mechanism by which it occurs in the brain, and its ultimate
place in the universe are unknown. We proposed in the mid 1990's that consciousness …

▪ Abstract The polymerization dynamics of microtubules are central to their biological
functions. Polymerization dynamics allow microtubules to adopt spatial arrangements that …

Microtubules are long, proteinaceous filaments that perform structural functions in eukaryotic
cells by defining cellular shape and serving as tracks for intracellular motor proteins. We …

Do biological motors move with regular steps? To address this question, we constructed
instrumentation with the spatial and temporal sensitivity to resolve movement on a molecular …

Features of consciousness difficult to understand in terms of conventional neuroscience
have evoked application of quantum theory, which describes the fundamental behavior of …

A high-resolution model of the microtubule has been obtained by docking the crystal
structure of tubulin into a 20 Å map of the microtubule. The excellent fit indicates the …

Controllable protein nanoarchitectonics refers to the process of manipulating and controlling
the assembly of proteins at the nanoscale to achieve domain‐limited and accurate spatial …

As we approach the three hundredth anniversary of the discovery of the spermatozoon
(1677) it seems timely to review what we know of the structure of this fascinating cell …

Here is a uniquely modern approach to the study of physiological diversity that builds on the
tradition established by C. Ladd Prosser's Comparative Animal Physiology. Responding to …

Chemical compounds that interfere with microtubules such as the vinca alkaloids and
taxanes are important chemotherapeutic agents for the treatment of cancer. As our …