[PDF][PDF] Low-density lipoproteins cause atherosclerotic cardiovascular disease: pathophysiological, genetic, and therapeutic insights: a consensus statement from the …
OP-EHEA191011_online 2313..2340 Page 1 Low-density lipoproteins cause atherosclerotic
cardiovascular disease: pathophysiological, genetic, and therapeutic insights: a consensus …
cardiovascular disease: pathophysiological, genetic, and therapeutic insights: a consensus …
High-density lipoprotein revisited: biological functions and clinical relevance
A von Eckardstein, BG Nordestgaard… - European heart …, 2023 - academic.oup.com
Previous interest in high-density lipoproteins (HDLs) focused on their possible protective
role in atherosclerotic cardiovascular disease (ASCVD). Evidence from genetic studies and …
role in atherosclerotic cardiovascular disease (ASCVD). Evidence from genetic studies and …
Cardiovascular disease in diabetes, beyond glucose
RH Eckel, KE Bornfeldt, IJ Goldberg - Cell metabolism, 2021 - cell.com
Despite the decades-old knowledge that diabetes mellitus is a major risk factor for
cardiovascular disease, the reasons for this association are only partially understood. While …
cardiovascular disease, the reasons for this association are only partially understood. While …
Serum cholesterol levels and risk of cardiovascular death: a systematic review and a dose-response meta-analysis of prospective cohort studies
Introduction: Numerous studies have demonstrated that abnormal levels of cholesterol are
associated with a high attributable risk for the occurrence of cardiovascular disease (CVD) …
associated with a high attributable risk for the occurrence of cardiovascular disease (CVD) …
Addressing dyslipidemic risk beyond LDL-cholesterol
AR Tall, DG Thomas… - The Journal of …, 2022 - Am Soc Clin Investig
Despite the success of LDL-lowering drugs in reducing cardiovascular disease (CVD), there
remains a large burden of residual disease due in part to persistent dyslipidemia …
remains a large burden of residual disease due in part to persistent dyslipidemia …
Cholesterol, inflammation and innate immunity
Hypercholesterolaemia leads to cholesterol accumulation in macrophages and other
immune cells, which promotes inflammatory responses, including augmentation of Toll-like …
immune cells, which promotes inflammatory responses, including augmentation of Toll-like …
[HTML][HTML] The role of lipids and lipoproteins in atherosclerosis
MRF Linton, PG Yancey, SS Davies, WG Jerome… - Endotext …, 2019 - ncbi.nlm.nih.gov
Atherosclerosis is the underlying cause of heart attack and stroke. Early observations that
cholesterol is a key component of arterial plaques gave rise to the cholesterol hypothesis for …
cholesterol is a key component of arterial plaques gave rise to the cholesterol hypothesis for …
Recommendation on design, execution, and reporting of animal atherosclerosis studies: a scientific statement from the American Heart Association
Animal studies are a foundation for defining mechanisms of atherosclerosis and potential
targets of drugs to prevent lesion development or reverse the disease. In the current …
targets of drugs to prevent lesion development or reverse the disease. In the current …
HDL and cardiovascular disease
DJ Rader, GK Hovingh - The Lancet, 2014 - thelancet.com
The cholesterol contained within HDL is inversely associated with risk of coronary heart
disease and is a key component of predicting cardiovascular risk. However, despite its …
disease and is a key component of predicting cardiovascular risk. However, despite its …
APOA1: a protein with multiple therapeutic functions
Abstract Purpose of the Review Apolipoprotein (APO) A1, the main apolipoprotein of plasma
high-density lipoproteins (HDLs), has several well documented cardioprotective functions. A …
high-density lipoproteins (HDLs), has several well documented cardioprotective functions. A …