Neoantigens: promising targets for cancer therapy

N **e, G Shen, W Gao, Z Huang, C Huang… - Signal transduction and …, 2023 - nature.com
Recent advances in neoantigen research have accelerated the development and regulatory
approval of tumor immunotherapies, including cancer vaccines, adoptive cell therapy and …

Cell penetrating peptides: classification, mechanisms, methods of study, and applications

A Gori, G Lodigiani, SG Colombarolli… - …, 2023 - Wiley Online Library
Cell‐penetrating peptides (CPPs) encompass a class of peptides that possess the
remarkable ability to cross cell membranes and deliver various types of cargoes, including …

Precision-engineering of subunit vaccine particles for prevention of infectious diseases

S Chen, S Pounraj, N Sivakumaran… - Frontiers in …, 2023 - frontiersin.org
Vaccines remain the best approach for the prevention of infectious diseases. Protein subunit
vaccines are safe compared to live-attenuated whole cell vaccines but often show reduced …

[HTML][HTML] Advancements and challenges in peptide-based cancer vaccination: a multidisciplinary perspective

D Liu, L Liu, X Li, S Wang, G Wu, X Che - Vaccines, 2024 - mdpi.com
With the continuous advancements in tumor immunotherapy, researchers are actively
exploring new treatment methods. Peptide therapeutic cancer vaccines have garnered …

Small Extracellular Vesicles Derived from Altered Peptide Ligand‐Loaded Dendritic Cell Act as A Therapeutic Vaccine for Spinal Cord Injury Through Eliciting CD4+ …

S Wang, G Li, X Liang, Z Wu, C Chen… - Advanced …, 2024 - Wiley Online Library
The balance among different CD4+ T cell subsets is crucial for repairing the injured spinal
cord. Dendritic cell (DC)‐derived small extracellular vesicles (DsEVs) effectively activate T …

Förster Resonance Energy Transfer Nanobullet for Photoacoustic Imaging and Amplified Photothermal‐Photodynamic Therapy of Cancer

M Tan, X Li, H Zhang, M Zheng, J **ong… - Advanced …, 2023 - Wiley Online Library
Synergistic photodynamic and photothermal therapy (PDT‐PTT) has emerged as an
appealing effective antitumor approach. However, clinical utilization of PDT‐PTT is plagued …

Cell penetrating peptide: A potent delivery system in vaccine development

B Hasannejad-Asl, F Pooresmaeil… - Frontiers in …, 2022 - frontiersin.org
One of the main obstacles to most medication administrations (such as the vaccine
constructs) is the cellular membrane's inadequate permeability, which reduces their …

Approaches for evaluation of novel CPP-based cargo delivery systems

L Porosk, Ü Langel - Frontiers in Pharmacology, 2022 - frontiersin.org
Cell penetrating peptides (CPPs) can be broadly defined as relatively short synthetic, protein
derived or chimeric peptides. Their most remarkable property is their ability to cross cell …

Polyphenol-Enabled 2D Nanopatch for Enhanced Nasal Mucoadhesion and Immune Activation

JP Han, YR Nam, HY Chung, H Lee, SC Yeom - Nano Letters, 2024 - ACS Publications
The advancement of effective nasal mucoadhesive delivery faces challenges due to rapid
mucociliary clearance (MCC). Conventional studies have employed mucoadhesive …

Light-responsive Au@ Zn-TCPP nanozyme functionalized with cell-penetrating peptide and antisense oligonucleotide for sensing living bacteria and synergistic …

X Zhang, Y Liu, Q Guo, S Yang, F Lan, J Du… - Chemical Engineering …, 2024 - Elsevier
The persistent bacterial infections in diabetic-induced wounds pose a significant societal
burden, requiring innovative antimicrobial agents and effective bacteria biosensor. In this …