Vascular mechanotransduction
This review aims to survey the current state of mechanotransduction in vascular smooth
muscle cells (VSMCs) and endothelial cells (ECs), including their sensing of mechanical …
muscle cells (VSMCs) and endothelial cells (ECs), including their sensing of mechanical …
TRP channels
Abstract The TRP (Transient Receptor Potential) superfamily of cation channels is
remarkable in that it displays greater diversity in activation mechanisms and selectivities …
remarkable in that it displays greater diversity in activation mechanisms and selectivities …
[HTML][HTML] Addition of docetaxel, zoledronic acid, or both to first-line long-term hormone therapy in prostate cancer (STAMPEDE): survival results from an adaptive …
Background Long-term hormone therapy has been the standard of care for advanced
prostate cancer since the 1940s. STAMPEDE is a randomised controlled trial using a …
prostate cancer since the 1940s. STAMPEDE is a randomised controlled trial using a …
Transient receptor potential cation channels in disease
The transient receptor potential (TRP) superfamily consists of a large number of cation
channels that are mostly permeable to both monovalent and divalent cations. The 28 …
channels that are mostly permeable to both monovalent and divalent cations. The 28 …
Transient receptor potential channels as drug targets: from the science of basic research to the art of medicine
The large Trp gene family encodes transient receptor potential (TRP) proteins that form
novel cation-selective ion channels. In mammals, 28 Trp channel genes have been …
novel cation-selective ion channels. In mammals, 28 Trp channel genes have been …
Renal autoregulation in health and disease
M Carlström, CS Wilcox… - Physiological …, 2015 - journals.physiology.org
Intrarenal autoregulatory mechanisms maintain renal blood flow (RBF) and glomerular
filtration rate (GFR) independent of renal perfusion pressure (RPP) over a defined range (80 …
filtration rate (GFR) independent of renal perfusion pressure (RPP) over a defined range (80 …
Mechanosensitive ion channels: structural features relevant to mechanotransduction mechanisms
P **, LY Jan, YN Jan - Annual review of neuroscience, 2020 - annualreviews.org
Activation of mechanosensitive ion channels underlies a variety of fundamental
physiological processes that require sensation of mechanical force. Different …
physiological processes that require sensation of mechanical force. Different …
Transient receptor potential channels in the vasculature
The mammalian genome encodes 28 distinct members of the transient receptor potential
(TRP) superfamily of cation channels, which exhibit varying degrees of selectivity for …
(TRP) superfamily of cation channels, which exhibit varying degrees of selectivity for …
Cell biology and pathology of podocytes
A Greka, P Mundel - Annual review of physiology, 2012 - annualreviews.org
As an integral member of the filtration barrier in the kidney glomerulus, the podocyte is in a
unique geographical position: It is exposed to chemical signals from the urinary space …
unique geographical position: It is exposed to chemical signals from the urinary space …
The role of transient receptor potential cation channels in Ca2+ signaling
M Gees, B Colsoul, B Nilius - Cold Spring Harbor …, 2010 - cshperspectives.cshlp.org
The 28 mammalian members of the super-family of transient receptor potential (TRP)
channels are cation channels, mostly permeable to both monovalent and divalent cations …
channels are cation channels, mostly permeable to both monovalent and divalent cations …