Oxidative damage in neurodegeneration: roles in the pathogenesis and progression of Alzheimer disease

M Perluigi, F Di Domenico… - Physiological …, 2024 - journals.physiology.org
Alzheimer disease (AD) is associated with multiple etiologies and pathological mechanisms,
among which oxidative stress (OS) appears as a major determinant. Intriguingly, OS arises …

Microbiome, probiotics and neurodegenerative diseases: deciphering the gut brain axis

S Westfall, N Lomis, I Kahouli, SY Dia, SP Singh… - Cellular and molecular …, 2017 - Springer
The gut microbiota is essential to health and has recently become a target for live bacterial
cell biotherapies for various chronic diseases including metabolic syndrome, diabetes …

[HTML][HTML] Antioxidant functionalized nanoparticles: A combat against oxidative stress

H Kumar, K Bhardwaj, E Nepovimova, K Kuča… - Nanomaterials, 2020 - mdpi.com
Numerous abiotic stresses trigger the overproduction of reactive oxygen species (ROS) that
are highly toxic and reactive. These ROS are known to cause damage to carbohydrates …

Antioxidant activity of nanomaterials

L Valgimigli, A Baschieri, R Amorati - Journal of Materials Chemistry B, 2018 - pubs.rsc.org
Nanomaterials represent one of the most promising frontiers in the research for improved
antioxidants. Some nanomaterials, including organic (ie melanin, lignin) metal oxides (ie …

Solid lipid nanoparticles as carriers of natural phenolic compounds

A Borges, V de Freitas, N Mateus, I Fernandes… - Antioxidants, 2020 - mdpi.com
Phenolic compounds are one of the most widespread classes of compounds in nature, with
several beneficial biological effects being associated with their anti-oxidant and anti …

Ferulic acid: pharmacological and toxicological aspects

C Mancuso, R Santangelo - Food and Chemical Toxicology, 2014 - Elsevier
Ferulic acid (FA) belongs to the family of phenolic acids and is very abundant in fruits and
vegetables. Over the past years, several studies have shown that FA acts as a potent …

Systematically designed chitosan-coated solid lipid nanoparticles of ferulic acid for effective management of Alzheimer's disease: A preclinical evidence

S Saini, T Sharma, A Jain, H Kaur, OP Katare… - Colloids and Surfaces B …, 2021 - Elsevier
Ferulic acid (FA) is a ubiquitous natural plant bioactive with distinctive promise in
neurodegenerative disorders. However, its therapeutic efficacy gets compromised owing to …

Alzheimer's disease and gut microbiota modifications: the long way between preclinical studies and clinical evidence

C Mancuso, R Santangelo - Pharmacological research, 2018 - Elsevier
Recent studies have suggested the role of an infectious component in the pathogenesis of
Alzheimer's disease (AD). In light of this, research has focused on some bacteria constituting …

Nanoformulations of herbal extracts in treatment of neurodegenerative disorders

SZ Moradi, S Momtaz, Z Bayrami… - … in bioengineering and …, 2020 - frontiersin.org
Nanotechnology is one of the methods that influenced human life in different ways and is a
substantial approach that assists to overcome the multiple limitations of various diseases …

[HTML][HTML] Anxiolytic-like Effects by trans-Ferulic Acid Possibly Occur through GABAergic Interaction Pathways

MS Bhuia, M Rokonuzzman, MI Hossain, SA Ansari… - Pharmaceuticals, 2023 - mdpi.com
Numerous previous studies reported that ferulic acid exerts anxiolytic activity. However, the
mechanisms have yet to be elucidated. The current study aimed to investigate the anxiolytic …