Reactive oxygen species, such as superoxide and hydrogen peroxide, are generated in all
cells by mitochondrial and enzymatic sources. Left unchecked, these reactive species can …

Arsenic (As) is widely used in the modern industry, especially in the production of pesticides,
herbicides, wood preservatives, and semiconductors. The sources of As such as …

The formation of micronuclei (MN) is extensively used in molecular epidemiology as a
biomarker of chromosomal damage, genome instability, and eventually of cancer risk. The …

Obesity is a multifactorial disease characterized by the excessive accumulation of fat in
adipose tissue and peripheral organs. Its derived metabolic complications are mediated by …

Oxidative stress develops as a result of an imbalance between the production and
accumulation of reactive species and the body's ability to manage them using exogenous …

Background: Reactive oxygen species (ROS) contribute to platelet hyperactivation during
aging. Several oxidative pathways and antioxidant enzymes have been implicated; …

Glaucoma is the leading cause of irreversible blindness worldwide. This review aims to
provide a greater understanding of the complex genetic influences that may lead to …

Purpose The antioxidant enzymes pathway is considered the most important pathway
involved in the repair of reactive oxygen species (ROS)–induced damage. Therefore, we …

Manganese superoxide dismutase (MnSOD), glutathione peroxidase-1 (GPX1), and
catalase (CAT) provide the primary antioxidant defense system. Impaired antioxidant …

Background There is growing evidence for the role of oxidative damage in chronic diseases.
Although ozone (O3) is an oxidant pollutant to which many people are exposed, few studies …