Chemistry of MRI contrast agents: current challenges and new frontiers

J Wahsner, EM Gale, A Rodríguez-Rodríguez… - Chemical …, 2018 - ACS Publications
Tens of millions of contrast-enhanced magnetic resonance imaging (MRI) exams are
performed annually around the world. The contrast agents, which improve diagnostic …

Spatial multiplexing and omics

JL Carstens, SN Krishnan, A Rao, AG Sorace… - Nature Reviews …, 2024 - nature.com
Much like solving a game of Clue, understanding physiological mysteries involves
answering who, what, when and where. Multiomics approaches delve into cellular and …

Activatable Fluorescence/MRI Bimodal Platform for Tumor Cell Imaging via MnO2 Nanosheet–Aptamer Nanoprobe

Z Zhao, H Fan, G Zhou, H Bai, H Liang… - Journal of the …, 2014 - ACS Publications
A novel dual-activatable fluorescence/MRI bimodal platform is designed for tumor cell
imaging by using a redoxable manganese dioxide (MnO2) nanosheet–aptamer nanoprobe …

Magnetic iron oxide nanoparticles as T 1 contrast agents for magnetic resonance imaging

Y Bao, JA Sherwood, Z Sun - Journal of Materials Chemistry C, 2018 - pubs.rsc.org
Ultrasmall iron oxide nanoparticles have recently attracted much attention as T1 (positive)
contrast agents for magnetic resonance imaging to serve as safer alternatives to gadolinium …

Macromolecules, dendrimers, and nanomaterials in magnetic resonance imaging: the interplay between size, function, and pharmacokinetics

AJL Villaraza, A Bumb, MW Brechbiel - Chemical reviews, 2010 - ACS Publications
Magnetism in medicine has had a long and interesting history. In the 10th century AD,
Egyptian physician and philosopher Avicenna prescribed a grain of magnetite dissolved in …

Surface impact on nanoparticle-based magnetic resonance imaging contrast agents

W Zhang, L Liu, H Chen, K Hu, I Delahunty… - …, 2018 - pmc.ncbi.nlm.nih.gov
Magnetic resonance imaging (MRI) is one of the most widely used diagnostic tools in the
clinic. To improve imaging quality, MRI contrast agents, which can modulate local T1 and T2 …

Size-Tunable, Ultrasmall NaGdF4 Nanoparticles: Insights into Their T1 MRI Contrast Enhancement

NJJ Johnson, W Oakden, GJ Stanisz… - Chemistry of …, 2011 - ACS Publications
We report on the size-tunable synthesis of thermodynamically stable (β) NaGdF4
nanoparticles (NPs) below 10 nm. Paramagnetic β-NaGdF4 NPs of four different sizes (2.5 …

Geometrical confinement of gadolinium-based contrast agents in nanoporous particles enhances T1 contrast

JS Ananta, B Godin, R Sethi, L Moriggi, X Liu… - Nature …, 2010 - nature.com
Magnetic resonance imaging contrast agents are currently designed by modifying their
structural and physiochemical properties to improve relaxivity and to enhance image …

Global structural optimization of tungsten borides

Q Li, D Zhou, W Zheng, Y Ma, C Chen - Physical Review Letters, 2013 - APS
Tungsten borides are among a distinct class of transition-metal light-element compounds
with superior mechanical properties that rival those of traditional superhard materials. An in …

Stimulus‐responsive nanoparticle magnetic resonance imaging contrast agents: design considerations and applications

S Fu, Z Cai, H Ai - Advanced Healthcare Materials, 2021 - Wiley Online Library
Magnetic resonance imaging (MRI) has been widely used for disease diagnosis because it
can noninvasively obtain anatomical details of various diseases through accurate contrast …