Major recent advances and previous data have led to a plausible model of how key proteins
mediate neurotransmitter release. In this model, the soluble N-ethylmaleimide-sensitive …

Soluble N-ethylmaleimide-sensitive factor attachment protein receptors (SNAREs) are a
family of small conserved eukaryotic proteins that mediate membrane fusion between …

The two universally required components of the intracellular membrane fusion machinery,
SNARE and SM (Sec1/Munc18-like) proteins, play complementary roles in fusion. Vesicular …

Diverse membrane fusion reactions in biology involve close contact between two lipid
bilayers, followed by the local distortion of the individual bilayers and reformation into a …

Neurotransmitter release is governed by proteins that have homo-logs in most types of
intracellular membrane fusion, including the Sec1/Munc18 protein Munc18-1 and the …

The complexity of biological membranes has motivated the development of a wide variety of
simpler model systems whose size, geometry, and composition can be tailored with great …

Lipids and several specialized proteins are thought to be able to sense the curvature of
membranes (MC). Here we used quantitative fluorescence microscopy to measure curvature …

Synthetic lipid–oligonucleotide conjugates inserted into lipid vesicles mediate fusion when
one population of vesicles displays the 5′-coupled conjugate and the other the 3 …

BAR (Bin/Amphiphysin/Rvs) domains and amphipathic α‐helices (AHs) are believed to be
sensors of membrane curvature thus facilitating the assembly of protein complexes on …

Cellular membrane fusion is thought to proceed through intermediates including docking of
apposed lipid bilayers, merging of proximal leaflets to form a hemifusion diaphragm, and …