Cytokinesis is the process by which mitotic cells physically split in two following
chromosome segregation. Dividing animal cells first ingress a cytokinetic furrow and then …

Epithelial–mesenchymal transitions (EMTs) are an important mechanism for reorganizing
germ layers and tissues during embryonic development. They have both a morphogenic …

© 2012 Marshall et al; licensee BioMed Central Ltd. This is an Open Access article
distributed under the terms of the Creative Commons Attribution License (http …

The mechanism underlying cytokinesis, the final step in cell division, remains one of the
major unsolved questions in basic cell biology. Thanks to advances in functional genomics …

Cytokinesis is the final step in cell division. The process begins during chromosome
segregation, when the ingressing cleavage furrow begins to partition the cytoplasm between …

Cells don't simply separate at cytokinesis. While furrow contraction critically relies on myosin-
II and F-actin, post-furrowing steps are less understood but involve the constriction of …

Dividing animal and plant cells maintain a constant chromosome content through temporally
separated rounds of replication and segregation. Until recently, the mechanisms by which …

Regulated exocytosis is a process in which the membranes of cytoplasmic organelles fuse
with the plasma membrane in response to stimulation. In many cases (secretory …

To ensure timely cytokinesis, the equatorial actomyosin contractile ring constricts at a
relatively constant rate despite its progressively decreasing size. Thus, the per-unit-length …

Membrane trafficking during cytokinesis is not well understood. We used advanced live cell
imaging techniques to track exocytosis of single vesicles to determine whether constitutively …