Bacteriophage resistance mechanisms

SJ Labrie, JE Samson, S Moineau - Nature Reviews Microbiology, 2010 - nature.com
Phages are now acknowledged as the most abundant microorganisms on the planet and
are also possibly the most diversified. This diversity is mostly driven by their dynamic …

CRISPR-Cas: biology, mechanisms and relevance

F Hille, E Charpentier - … of the royal society B: biological …, 2016 - royalsocietypublishing.org
Prokaryotes have evolved several defence mechanisms to protect themselves from viral
predators. Clustered regularly interspaced short palindromic repeats (CRISPR) and their …

Prophages mediate defense against phage infection through diverse mechanisms

J Bondy-Denomy, J Qian, ER Westra… - The ISME …, 2016 - academic.oup.com
The activity of bacteriophages poses a major threat to bacterial survival. Upon infection, a
temperate phage can either kill the host cell or be maintained as a prophage. In this state …

Evolutionary ecology of prokaryotic immune mechanisms

S van Houte, A Buckling, ER Westra - Microbiology and Molecular …, 2016 - Am Soc Microbiol
Bacteria have a range of distinct immune strategies that provide protection against
bacteriophage (phage) infections. While much has been learned about the mechanism of …

Non‐antibiotic approaches to combat motile Aeromonas infections in aquaculture: Current state of knowledge and future perspectives

LT Dien, TPH Ngo, TV Nguyen… - Reviews in …, 2023 - Wiley Online Library
Inland aquaculture contributed by three major fish groups, including carps, tilapias, and
catfish plays a vital role in global food security and nutrition, particularly in low and middle …

Remarkable mechanisms in microbes to resist phage infections

RL Dy, C Richter, GPC Salmond… - Annual review of …, 2014 - annualreviews.org
Bacteriophages (phages) specifically infect bacteria and are the most abundant biological
entities on Earth. The constant exposure to phage infection imposes a strong selective …

The human gut phageome: origins and roles in the human gut microbiome

EM Townsend, L Kelly, G Muscatt, JD Box… - Frontiers in cellular …, 2021 - frontiersin.org
The investigation of the microbial populations of the human body, known as the microbiome,
has led to a revolutionary field of science, and understanding of its impacts on human …

Temperate phage-antibiotic synergy eradicates bacteria through depletion of lysogens

AM Al-Anany, R Fatima, AP Hynes - Cell Reports, 2021 - cell.com
There is renewed interest in bacterial viruses (phages) as alternatives to antibiotics. All
phage treatments to date have used virulent phages rather than temperate ones, as these …

When a virus is not a parasite: the beneficial effects of prophages on bacterial fitness

J Bondy-Denomy, AR Davidson - Journal of microbiology, 2014 - Springer
Most organisms on the planet have viruses that infect them. Viral infection may lead to cell
death, or to a symbiotic relationship where the genomes of both virus and host replicate …

Phage defence loci of Streptococcus thermophilus—tip of the anti-phage iceberg?<?mode longmeta?>

P Kelleher, G Ortiz Charneco, Z Kampff… - Nucleic Acids …, 2024 - academic.oup.com
Bacteria possess (bacterio) phage defence systems to ensure their survival. The
thermophilic lactic acid bacterium, Streptococcus thermophilus, which is used in dairy …