Updates to the modern diagnosis of GERD: Lyon consensus 2.0
The Lyon Consensus provides conclusive criteria for and against the diagnosis of gastro-
oesophageal reflux disease (GERD), and adjunctive metrics that consolidate or refute GERD …
oesophageal reflux disease (GERD), and adjunctive metrics that consolidate or refute GERD …
Functional esophageal disorders
JP Galmiche, RE Clouse, A Balint, IJ Cook, PJ Kahrilas… - Gastroenterology, 2006 - Elsevier
Functional esophageal disorders represent processes accompanied by typical esophageal
symptoms (heartburn, chest pain, dysphagia, globus) that are not explained by structural …
symptoms (heartburn, chest pain, dysphagia, globus) that are not explained by structural …
GWAS of peptic ulcer disease implicates Helicobacter pylori infection, other gastrointestinal disorders and depression
Genetic factors are recognized to contribute to peptic ulcer disease (PUD) and other
gastrointestinal diseases, such as gastro-oesophageal reflux disease (GORD), irritable …
gastrointestinal diseases, such as gastro-oesophageal reflux disease (GORD), irritable …
Esophageal disorders
Functional esophageal disorders consist of a disease category that presents with
esophageal symptoms (heartburn, chest pain, dysphagia, globus) that are not explained by …
esophageal symptoms (heartburn, chest pain, dysphagia, globus) that are not explained by …
[HTML][HTML] Randomized trial of medical versus surgical treatment for refractory heartburn
SJ Spechler, JG Hunter, KM Jones, R Lee… - … England Journal of …, 2019 - Mass Medical Soc
Background Heartburn that persists despite proton-pump inhibitor (PPI) treatment is a
frequent clinical problem with multiple potential causes. Treatments for PPI-refractory …
frequent clinical problem with multiple potential causes. Treatments for PPI-refractory …
Systematic review: proton‐pump inhibitor failure in gastro‐oesophageal reflux disease–where next?
R Fass, M Shapiro, R Dekel… - Alimentary pharmacology …, 2005 - Wiley Online Library
Proton‐pump inhibitor failure has become a common clinical dilemma in gastrointestinal
clinics and has been increasingly encountered at the primary care level as well. Underlying …
clinics and has been increasingly encountered at the primary care level as well. Underlying …
NERD: an umbrella term including heterogeneous subpopulations
Nonerosive reflux disease (NERD) represents the more common phenotypic presentation of
GERD and comprises patients who have typical symptoms without any mucosal breaks at …
GERD and comprises patients who have typical symptoms without any mucosal breaks at …
A placebo-controlled trial of acotiamide for meal-related symptoms of functional dyspepsia
K Matsueda, M Hongo, J Tack, Y Saito, H Kato - Gut, 2012 - gut.bmj.com
Objective To determine the efficacy of acotiamide, an acetylcholinesterase inhibitor, in
patients with functional dyspepsia (FD) in a 4-week trial Methods A multicentre, randomised …
patients with functional dyspepsia (FD) in a 4-week trial Methods A multicentre, randomised …
Canadian Consensus Conference on the management of gastroesophageal reflux disease in adults–update 2004
BACKGROUND: Gastroesophageal reflux disease (GERD) is the most prevalent acid‐
related disorder in Canada and is associated with significant impairment of health‐related …
related disorder in Canada and is associated with significant impairment of health‐related …
Determinants of perception of heartburn and regurgitation
Background and aim: It is not known why some reflux episodes evoke symptoms and others
do not. We investigated the determinants of perception of gastro-oesophageal reflux …
do not. We investigated the determinants of perception of gastro-oesophageal reflux …