Prediction models for diagnosis and prognosis of covid-19: systematic review and critical appraisal

L Wynants, B Van Calster, GS Collins, RD Riley… - bmj, 2020 - bmj.com
Objective To review and appraise the validity and usefulness of published and preprint
reports of prediction models for prognosis of patients with covid-19, and for detecting people …

Evaluation of clinical prediction models (part 1): from development to external validation

GS Collins, P Dhiman, J Ma, MM Schlussel, L Archer… - Bmj, 2024 - bmj.com
Evaluating the performance of a clinical prediction model is crucial to establish its predictive
accuracy in the populations and settings intended for use. In this article, the first in a three …

Genomic characteristics and clinical effect of the emergent SARS-CoV-2 B. 1.1. 7 lineage in London, UK: a whole-genome sequencing and hospital-based cohort …

D Frampton, T Rampling, A Cross, H Bailey… - The Lancet infectious …, 2021 - thelancet.com
Background Emergence of variants with specific mutations in key epitopes in the spike
protein of SARS-CoV-2 raises concerns pertinent to mass vaccination campaigns and use of …

Long Covid in adults discharged from UK hospitals after Covid-19: A prospective, multicentre cohort study using the ISARIC WHO Clinical Characterisation Protocol

L Sigfrid, TM Drake, E Pauley… - The Lancet Regional …, 2021 - thelancet.com
Background This study sought to establish the long-term effects of Covid-19 following
hospitalisation. Methods 327 hospitalised participants, with SARS-CoV-2 infection were …

Effective prognostic and clinical risk stratification in COVID‐19 using multimodality biomarkers

A Liu, R Hammond, PD Donnelly… - Journal of Internal …, 2023 - Wiley Online Library
In acute coronavirus disease 19 (COVID‐19) patients, effective clinical risk stratification has
important implications on treatment and therapeutic resource distribution. This article …

Transparent reporting of multivariable prediction models for individual prognosis or diagnosis: checklist for systematic reviews and meta-analyses (TRIPOD-SRMA)

KIE Snell, B Levis, JAA Damen, P Dhiman, TPA Debray… - Bmj, 2023 - bmj.com
Most clinical specialties have a plethora of studies that develop or validate one or more
prediction models, for example, to inform diagnosis or prognosis. Having many prediction …

Remote management of covid-19 using home pulse oximetry and virtual ward support

T Greenhalgh, M Knight, M Inada-Kim, NJ Fulop… - bmj, 2021 - bmj.com
Low blood oxygen—technically, hypoxaemia but usually referred to as hypoxia—can be
defined as a measured oxygen saturation below 94% in the absence (or below 88% in the …

Evaluation of clinical prediction models (part 3): calculating the sample size required for an external validation study

RD Riley, KIE Snell, L Archer, J Ensor, TPA Debray… - bmj, 2024 - bmj.com
An external validation study evaluates the performance of a prediction model in new data,
but many of these studies are too small to provide reliable answers. In the third article of their …

Allocating scarce intensive care resources during the COVID-19 pandemic: practical challenges to theoretical frameworks

A Supady, JR Curtis, D Abrams, R Lorusso… - The Lancet …, 2021 - thelancet.com
The COVID-19 pandemic strained health-care systems throughout the world. For some,
available medical resources could not meet the increased demand and rationing was …

Circulating microRNA signatures associated with disease severity and outcome in COVID-19 patients

A Giannella, S Riccetti, A Sinigaglia, C Piubelli… - Frontiers in …, 2022 - frontiersin.org
Background SARS-CoV-2 induces a spectrum of clinical conditions ranging from
asymptomatic infection to life threatening severe disease. Host microRNAs have been …