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The role of platelets in immune-mediated inflammatory diseases
Immune-mediated inflammatory diseases (IMIDs) are characterized by excessive and
uncontrolled inflammation and thrombosis, both of which are responsible for organ damage …
uncontrolled inflammation and thrombosis, both of which are responsible for organ damage …
COVID-19 update: Covid-19-associated coagulopathy
RC Becker - Journal of thrombosis and thrombolysis, 2020 - Springer
The Covid-19 pandemic has introduced an array of organspecific and systemic phenotypes-
some previously observed in viral infections, including severe acute respiratory syndrome …
some previously observed in viral infections, including severe acute respiratory syndrome …
[HTML][HTML] Elevated calprotectin and abnormal myeloid cell subsets discriminate severe from mild COVID-19
Blood myeloid cells are known to be dysregulated in coronavirus disease 2019 (COVID-19),
caused by SARS-CoV-2. It is unknown whether the innate myeloid response differs with …
caused by SARS-CoV-2. It is unknown whether the innate myeloid response differs with …
Mechanism of thrombocytopenia in COVID-19 patients
P Xu, Q Zhou, J Xu - Annals of hematology, 2020 - Springer
Since December 2019, a novel coronavirus has spread throughout China and across the
world, causing a continuous increase in confirmed cases within a short period of time. Some …
world, causing a continuous increase in confirmed cases within a short period of time. Some …
COVID-19 and multiorgan failure: A narrative review on potential mechanisms
The outbreak of severe acute respiratory syndrome coronavirus 2 (SARS-CoV2) in
December 2019 form Wuhan, China leads to coronavirus disease 2019 (COVID-19) …
December 2019 form Wuhan, China leads to coronavirus disease 2019 (COVID-19) …
Thrombocytopathy and endotheliopathy: crucial contributors to COVID-19 thromboinflammation
The core pathology of coronavirus disease 2019 (COVID-19) is infection of airway cells by
severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that results in excessive …
severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that results in excessive …
Platelet factors are induced by longevity factor klotho and enhance cognition in young and aging mice
Platelet factors regulate wound healing and can signal from the blood to the brain,.
However, whether platelet factors modulate cognition, a highly valued and central …
However, whether platelet factors modulate cognition, a highly valued and central …
[HTML][HTML] Platelets contribute to disease severity in COVID‐19
Objective Heightened inflammation, dysregulated immunity, and thrombotic events are
characteristic of hospitalized COVID‐19 patients. Given that platelets are key regulators of …
characteristic of hospitalized COVID‐19 patients. Given that platelets are key regulators of …
The neutrophil's role during health and disease
Neutrophils have always been considered as uncomplicated front-line troopers of the innate
immune system equipped with limited proinflammatory duties. Yet recently, the role of the …
immune system equipped with limited proinflammatory duties. Yet recently, the role of the …
In vivo editing of lung stem cells for durable gene correction in mice
In vivo genome correction holds promise for generating durable disease cures; yet, effective
stem cell editing remains challenging. In this work, we demonstrate that optimized lung …
stem cell editing remains challenging. In this work, we demonstrate that optimized lung …