Lipid-based drug delivery systems in cancer therapy: what is available and what is yet to come

P Yingchoncharoen, DS Kalinowski… - Pharmacological …, 2016 - Elsevier
Cancer is a leading cause of death in many countries around the world. However, the
efficacy of current standard treatments for a variety of cancers is suboptimal. First, most …

Strategies to address low drug solubility in discovery and development

HD Williams, NL Trevaskis, SA Charman… - Pharmacological …, 2013 - Elsevier
Drugs with low water solubility are predisposed to low and variable oral bioavailability and,
therefore, to variability in clinical response. Despite significant efforts to “design in” …

Functionalizing nanoparticles with biological molecules: develo** chemistries that facilitate nanotechnology

KE Sapsford, WR Algar, L Berti, KB Gemmill… - Chemical …, 2013 - ACS Publications
(5aR, 11bS)-4, 5, 5a, 6, 7, 11b-Hexahydro-2-propyl-3-thia-5-azacyclopent-1-ena [c]
phenanthrene-9, 10-diol (A-86929): a potent and selective dopamine D1 agonist that …

Solid lipid nanoparticles as carriers of natural phenolic compounds

A Borges, V de Freitas, N Mateus, I Fernandes… - Antioxidants, 2020 - mdpi.com
Phenolic compounds are one of the most widespread classes of compounds in nature, with
several beneficial biological effects being associated with their anti-oxidant and anti …

Solid lipid nanoparticles for targeted natural and synthetic drugs delivery in high-incidence cancers, and other diseases: Roles of preparation methods, lipid …

HA Mohammed, RA Khan, V Singh, M Yusuf… - Nanotechnology …, 2023 - degruyter.com
Solid lipid nanoparticles (SLNs), the spheroidal-shaped, colloids state lipophilic-natured,
innovative nanoscale particulate materials, are being concurrently prepared by the quality …

Solid lipid nanoparticles: a modern formulation approach in drug delivery system

S Mukherjee, S Ray, RS Thakur - Indian journal of …, 2009 - pmc.ncbi.nlm.nih.gov
Solid lipid nanoparticles are at the forefront of the rapidly develo** field of nanotechnology
with several potential applications in drug delivery, clinical medicine and research, as well …

Importance of solid lipid nanoparticles (SLN) in various administration routes and future perspectives

M Üner, G Yener - International journal of nanomedicine, 2007 - Taylor & Francis
Solid lipid nanoparticles (SLN) have been reported to be an alternative system to emulsions,
liposomes, microparticles and their polymeric counterparts for various application routes …

Organic nanoparticles in the aqueous phase—theory, experiment, and use

D Horn, J Rieger - Angewandte Chemie International Edition, 2001 - Wiley Online Library
Many active organic compounds and organic effect materials are poorly soluble in water, or
even insoluble. Aqueous forms of application thus require special formulation techniques to …

Recent progress in nanomaterials for gene delivery applications

E Keles, Y Song, D Du, WJ Dong, Y Lin - Biomaterials science, 2016 - pubs.rsc.org
Nanotechnology-based gene delivery is the division of nanomedicine concerned with the
synthesis, characterization, and functionalization of nanomaterials to be used in targeted …