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Strategies for overcoming protein and peptide instability in biodegradable drug delivery systems
The global pharmaceutical market has recently shifted its focus from small molecule drugs to
peptide, protein, and nucleic acid drugs, which now comprise a majority of the top-selling …
peptide, protein, and nucleic acid drugs, which now comprise a majority of the top-selling …
Thermostable vaccines: An innovative concept in vaccine development
Introduction Vaccines represent he most common and safer ways of combating infectious
diseases. Loss of potency owing to thermal denaturation or degradation of almost all the …
diseases. Loss of potency owing to thermal denaturation or degradation of almost all the …
Blockchain-based solution for distribution and delivery of COVID-19 vaccines
Distribution and delivery of Coronavirus 2019 (COVID-19) vaccines have become
challenging after their emergence. Today's platforms and systems leveraged for managing …
challenging after their emergence. Today's platforms and systems leveraged for managing …
Thermal stabilization of diverse biologics using reversible hydrogels
Improving the thermal stability of biologics, including vaccines, is critical to reduce the
economic costs and health risks associated with the cold chain. Here, we designed a …
economic costs and health risks associated with the cold chain. Here, we designed a …
The vaccine supply chain: a call for resilience analytics to support COVID-19 vaccine production and distribution
Pharmaceutical companies, upstream suppliers, associated logistics providers, health
workers, regulatory agencies, public health experts and ultimately the medical practitioners …
workers, regulatory agencies, public health experts and ultimately the medical practitioners …
[HTML][HTML] Biomimetic metal-organic frameworks as protective scaffolds for live-virus encapsulation and vaccine stabilization
The invaluable health, economic and social impacts of vaccination are hard to exaggerate.
The ability to stabilize vaccines is urgently required for their equitable distribution without the …
The ability to stabilize vaccines is urgently required for their equitable distribution without the …
[HTML][HTML] Transforming vaccine development
The urgency to develop vaccines against Covid-19 is putting pressure on the long and
expensive development timelines that are normally required for development of lifesaving …
expensive development timelines that are normally required for development of lifesaving …
Development of a formulation platform for a spray-dried, inhalable tuberculosis vaccine candidate
Protection against primarily respiratory infectious diseases, such as tuberculosis (TB), can
likely be enhanced through mucosal immunization induced by direct delivery of vaccines to …
likely be enhanced through mucosal immunization induced by direct delivery of vaccines to …
An efficient (nano) silica-In glucan particles protein encapsulation approach for improved thermal stability
ER Soto, CA Specht, F Rus, CK Lee, A Abraham… - Journal of Controlled …, 2023 - Elsevier
Glucan particles (GPs) are hollow, porous microspheres derived from Saccharomyces
cerevisiae (Baker's yeast). The hollow cavity of GPs allows for efficient encapsulation of …
cerevisiae (Baker's yeast). The hollow cavity of GPs allows for efficient encapsulation of …
[HTML][HTML] Development of stabilizing solution for long-term storage of bacteriophages at room temperature and application to control foodborne pathogens
Bacteriophages (phages) have gained considerable attention as effective antimicrobial
agents that infect and kill pathogenic bacteria. Based on this feature, phages have been …
agents that infect and kill pathogenic bacteria. Based on this feature, phages have been …