Sharing vitamins: Cobamides unveil microbial interactions

OM Sokolovskaya, AN Shelton, ME Taga - Science, 2020 - science.org
BACKGROUND Nearly every plant, animal, and environment on earth is host to a diverse
community of microorganisms that influence each other and their environment …

Decoding molecular interactions in microbial communities

NA Abreu, ME Taga - FEMS Microbiology Reviews, 2016 - academic.oup.com
Microbial communities govern numerous fundamental processes on earth. Discovering and
tracking molecular interactions among microbes is critical for understanding how single …

Uneven distribution of cobamide biosynthesis and dependence in bacteria predicted by comparative genomics

AN Shelton, EC Seth, KC Mok, AW Han… - The ISME …, 2019 - academic.oup.com
The vitamin B12 family of cofactors known as cobamides are essential for a variety of
microbial metabolisms. We used comparative genomics of 11,000 bacterial species to …

Ligand cross-feeding resolves bacterial vitamin B12 auxotrophies

G Wienhausen, C Moraru, S Bruns, DQ Tran, S Sultana… - Nature, 2024 - nature.com
Cobalamin (vitamin B12, herein referred to as B12) is an essential cofactor for most marine
prokaryotes and eukaryotes,. Synthesized by a limited number of prokaryotes, its scarcity …

Cyanobacteria and eukaryotic algae use different chemical variants of vitamin B12

KE Helliwell, AD Lawrence, A Holzer, UJ Kudahl… - Current Biology, 2016 - cell.com
Eukaryotic microalgae and prokaryotic cyanobacteria are the major components of the
phytoplankton. Determining factors that govern growth of these primary producers, and how …

Metagenomics-guided analysis of microbial chemolithoautotrophic phosphite oxidation yields evidence of a seventh natural CO2 fixation pathway

IA Figueroa, TP Barnum, PY Somasekhar… - Proceedings of the …, 2018 - pnas.org
Dissimilatory phosphite oxidation (DPO), a microbial metabolism by which phosphite
(HPO32−) is oxidized to phosphate (PO43−), is the most energetically favorable …

Metagenomic and chemical characterization of soil cobalamin production

X Lu, KR Heal, AE Ingalls, AC Doxey… - The ISME …, 2020 - academic.oup.com
Cobalamin (vitamin B12) is an essential enzyme cofactor for most branches of life. Despite
the potential importance of this cofactor for soil microbial communities, the producers and …

Extreme allelic heterogeneity at a Caenorhabditis elegans beta-tubulin locus explains natural resistance to benzimidazoles

SR Hahnel, S Zdraljevic, BC Rodriguez, Y Zhao… - PLoS …, 2018 - journals.plos.org
Benzimidazoles (BZ) are essential components of the limited chemotherapeutic arsenal
available to control the global burden of parasitic nematodes. The emerging threat of BZ …

Availability of vitamin B12 and its lower ligand intermediate α-ribazole impact prokaryotic and protist communities in oceanic systems

G Wienhausen, L Dlugosch, R Jarling… - The ISME …, 2022 - academic.oup.com
Genome analyses predict that the cofactor cobalamin (vitamin B12, called B12 herein) is
produced by only one-third of all prokaryotes but almost all encode at least one B12 …

Overview of known organohalide-respiring bacteria—phylogenetic diversity and environmental distribution

S Atashgahi, Y Lu, H Smidt - Organohalide-respiring bacteria, 2016 - Springer
To date, organohalide respiration (OHR) has been restricted to the bacterial domain of life.
Known organohalide-respiring bacteria (OHRB) are spread among several phyla …