Membrane trafficking between organelles by vesiculotubular carriers is fundamental to the
existence of eukaryotic cells. Central in ensuring that cargoes are delivered to their correct …

Cellular organelles in the exocytic and endocytic pathways have a distinctive spatial
distribution and communicate through an elaborate system of vesiculo-tubular transport …

Exosomes are generated within the multivesicular endosomes (MVEs) as intraluminal
vesicles (ILVs) and secreted during the fusion of MVEs with the cell membrane. The …

Macrophages and neutrophils play a decisive role in host responses to intracellular bacteria
including the agent of tuberculosis (TB), M ycobacterium tuberculosis as they represent the …

Small GTP-binding proteins (G proteins) exist in eukaryotes from yeast to human and
constitute a superfamily consisting of more than 100 members. This superfamily is …

Intracellular membrane traffic defines a complex network of pathways that connects many of
the membrane-bound organelles of eukaryotic cells. Although each pathway is governed by …

Phosphoinositides (PIs) make up only a small fraction of cellular phospholipids, yet they
control almost all aspects of a cell's life and death. These lipids gained tremendous research …

Zinc (Zn) nutritional importance has been known for a long time, but in the last decades its
importance in immune modulation has arisen. This review aims at describing the …

Engulfment and destruction of invading microorganisms by phagocytosis are critical
components of the innate immune response. In addition, phagocytosis is also required for …

Over the past two decades, our understanding of phospoinositide 3-kinases (PI3Ks) has
progressed from the identification of an enzymatic activity associated with growth factors …