Collective cell migration in development

E Scarpa, R Mayor - Journal of cell Biology, 2016 - rupress.org
During embryonic development, tissues undergo major rearrangements that lead to germ
layer positioning, patterning, and organ morphogenesis. Often these morphogenetic …

Dynamic contacts: rearranging adherens junctions to drive epithelial remodelling

M Takeichi - Nature reviews Molecular cell biology, 2014 - nature.com
Epithelial cells display dynamic behaviours, such as rearrangement, movement and shape
changes, particularly during embryonic development and in equivalent processes in adults …

Tensile forces govern germ-layer organization in zebrafish

M Krieg, Y Arboleda-Estudillo, PH Puech, J Käfer… - Nature cell …, 2008 - nature.com
Understanding the factors that direct tissue organization during development is one of the
most fundamental goals in developmental biology. Various hypotheses explain cell sorting …

Fibronectins, their fibrillogenesis, and in vivo functions

JE Schwarzbauer… - Cold Spring Harbor …, 2011 - cshperspectives.cshlp.org
Fibronectin (FN) is a multidomain protein with the ability to bind simultaneously to cell
surface receptors, collagen, proteoglycans, and other FN molecules. Many of these domains …

Single-cell force spectroscopy

J Helenius, CP Heisenberg, HE Gaub… - Journal of cell …, 2008 - journals.biologists.com
The controlled adhesion of cells to each other and to the extracellular matrix is crucial for
tissue development and maintenance. Numerous assays have been developed to quantify …

Tissue organization by cadherin adhesion molecules: dynamic molecular and cellular mechanisms of morphogenetic regulation

CM Niessen, D Leckband, AS Yap - Physiological reviews, 2011 - journals.physiology.org
This review addresses the cellular and molecular mechanisms of cadherin-based tissue
morphogenesis. Tissue physiology is profoundly influenced by the distinctive organizations …

Chase-and-run between adjacent cell populations promotes directional collective migration

E Theveneau, B Steventon, E Scarpa, S Garcia… - Nature cell …, 2013 - nature.com
Collective cell migration in morphogenesis and cancer progression often involves the
coordination of multiple cell types. How reciprocal interactions between adjacent cell …

Atomic force microscopy-based characterization and design of biointerfaces

D Alsteens, HE Gaub, R Newton… - Nature Reviews …, 2017 - nature.com
Atomic force microscopy (AFM)-based methods have matured into a powerful nanoscopic
platform, enabling the characterization of a wide range of biological and synthetic …

Wnt signaling pathways meet Rho GTPases

K Schlessinger, A Hall, N Tolwinski - Genes & development, 2009 - genesdev.cshlp.org
Wnt ligands and their receptors orchestrate many essential cellular and physiological
processes. During development they control differentiation, proliferation, migration, and …

Hexagonal packing of Drosophila wing epithelial cells by the planar cell polarity pathway

AK Classen, KI Anderson, E Marois, S Eaton - Developmental cell, 2005 - cell.com
The mechanisms that order cellular packing geometry are critical for the functioning of many
tissues, but they are poorly understood. Here, we investigate this problem in the develo** …