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Emerging concepts of type I interferons in SLE pathogenesis and therapy
Type I interferons have been suspected for decades to have a crucial role in the
pathogenesis of systemic lupus erythematosus (SLE). Evidence has now overturned several …
pathogenesis of systemic lupus erythematosus (SLE). Evidence has now overturned several …
Interdisciplinary gene manipulation, molecular cloning, and recombinant expression of modified human growth hormone isoform-1 in E. coli system
Background Growth hormone (GH) is a hormone that promotes growth, cell reproduction,
and cell restoration in humans and animals. Objectives Production of recombinant human …
and cell restoration in humans and animals. Objectives Production of recombinant human …
Urinary biomarkers analysis as a diagnostic tool for early detection of pancreatic adenocarcinoma: molecular quantification approach
Background and aims Pancreatic ductal adenocarcinoma (PDAC) is infrequent. Currently,
non-invasive biomarkers for early detection of PDAC are not accessible. Here, we intended …
non-invasive biomarkers for early detection of PDAC are not accessible. Here, we intended …
Phages for treatment of Staphylococcus aureus infection
S Samir - Progress in Molecular Biology and Translational …, 2023 - Elsevier
Combating multi-drug resistant bacterial infections should be a universal urgency. The gram-
positive Staphylococcus aureus (S. aureus) bacteria are generally harmless; healthy people …
positive Staphylococcus aureus (S. aureus) bacteria are generally harmless; healthy people …
Purified recombinant human Chromogranin A N46 peptide with remarkable anticancer effect on human colon cancer cells
Abstract Human Chromogranin A N46 (CGA-N46) is a weak cationic α-helical peptide with
wide-spectrum antibacterial, fungal, and anticancer activities. In this study, the recombinant …
wide-spectrum antibacterial, fungal, and anticancer activities. In this study, the recombinant …
Soluble receptor isoform of IFN-beta (sIFNAR2) in multiple sclerosis patients and their association with the clinical response to IFN-beta treatment
P Aliaga-Gaspar, I Hurtado-Guerrero… - Frontiers in …, 2021 - frontiersin.org
Purpose Interferon beta receptor 2 subunit (IFNAR2) can be produced as a transmembrane
protein, but also as a soluble form (sIFNAR2) generated by alternative splicing or proteolytic …
protein, but also as a soluble form (sIFNAR2) generated by alternative splicing or proteolytic …
Development of a Novel Peptide with RGD Tumor Homing Motif: Evaluation of its Anticancer Potential in Hepatocellular Carcinoma and Colon Cancer Cells
RA Mohamed, OM Marie, DI Badran… - Recent Patents on …, 2025 - benthamdirect.com
Background Peptide-based therapy has emerged as a promising avenue for treating various
disorders, and recent research has highlighted the potential of anti-cancer peptides (ACPs) …
disorders, and recent research has highlighted the potential of anti-cancer peptides (ACPs) …
[HTML][HTML] GC-MS analysis, anti-inflammatory and anti-proliferative properties of the aerial parts of three Mesembryanthemum spp.
Background Due to their variability and safety, widespread research on phytochemicals
continually encourages researchers to study various plants for their potential health benefits …
continually encourages researchers to study various plants for their potential health benefits …
[HTML][HTML] Identification and exploration of anticancer activity of novel peptides isolated from the edible bivalve Callista chione in hepatic and colon cancer cell lines
Background The requirement for relevant and safe drugs for cancer treatment is considered
a challenge. Recently, marine isolated compounds with various therapeutic targets have …
a challenge. Recently, marine isolated compounds with various therapeutic targets have …
Assessing the diagnostic potential of SATB2 and β-catenin as biomarkers and therapeutic targets in pancreatic ductal adenocarcinoma
Methods We analyzed 44 paraffin-embedded tissue blocks along with corresponding blood
and pancreatic tissues. We evaluated SATB2 expression using immunohistochemistry (IHC) …
and pancreatic tissues. We evaluated SATB2 expression using immunohistochemistry (IHC) …