Gene–stress–epigenetic regulation of FKBP5: clinical and translational implications

AS Zannas, T Wiechmann, NC Gassen… - …, 2016 - nature.com
Stress responses and related outcomes vary markedly across individuals. Elucidating the
molecular underpinnings of this variability is of great relevance for develo** individualized …

Interaction between early-life stress and FKBP5 gene variants in major depressive disorder and post-traumatic stress disorder: A systematic review and meta-analysis

Q Wang, RC Shelton, Y Dwivedi - Journal of affective disorders, 2018 - Elsevier
Background Gene-environment interaction contributes to the risks of psychiatric disorders.
Interactions between FKBP5 gene variants and early-life stress may enhance the risk not …

Posttraumatic growth in populations with posttraumatic stress disorder—A systematic review on growth‐related psychological constructs and biological variables

CF Schubert, U Schmidt… - Clinical psychology & …, 2016 - Wiley Online Library
Posttraumatic growth (PTG) and Posttraumatic Stress Disorder (PTSD) are possible
consequences of trauma. PTG is supposed to emerge from cognitive processes and can …

Genomics and psychological resilience: a research agenda

KW Choi, MB Stein, EC Dunn, KC Koenen… - Molecular …, 2019 - nature.com
Although exposure to adversity increases risk for poor mental health outcomes, many
people exposed to adversity do not develop such outcomes. Psychological resilience …

Gene× environment determinants of stress-and anxiety-related disorders

S Sharma, A Powers, B Bradley… - Annual review of …, 2016 - annualreviews.org
The burgeoning field of gene-by-environment (G× E) interactions has revealed fascinating
biological insights, particularly in the realm of stress-, anxiety-, and depression-related …

The associations between oxytocin and trauma in humans: a systematic review

MF Donadon, R Martin-Santos, FL Osorio - Frontiers in pharmacology, 2018 - frontiersin.org
Studies have shown that traumatic experiences may affect hormonal systems mediated by
the hypothalamic-pituitary-adrenal (HPA) axis and the oxytocinergic system. This effect is the …

Posttraumatic stress in patients with inflammatory bowel disease: prevalence and relationships to patient-reported outcomes

TH Taft, S Quinton, S Jedel, M Simons… - Inflammatory bowel …, 2022 - academic.oup.com
Background Patients with chronic illness are at increased risk for traumatic stress because of
medical trauma. Initial studies of posttraumatic stress (PTS) in patients with inflammatory …

The compelling dynamics of “will to exist, live, and survive” on effecting posttraumatic growth upon exposure to adversities: Is it mediated, in part, by emotional …

IA Kira, N Arıcı Özcan, H Shuwiekh, J Kucharska… - Traumatology, 2020 - psycnet.apa.org
The goal of the current study is to empirically examine the role of a person's will to exist, live,
and survive (WTELS) in growth upon exposure to cumulative stressors and traumas (CST) …

Biological underpinnings of trauma and post-traumatic stress disorder: focusing on genetics and epigenetics

J Ryan, I Chaudieu, ML Ancelin, R Saffery - Epigenomics, 2016 - Taylor & Francis
Certain individuals are more susceptible to stress and trauma, as well as the physical and
mental health consequences following such exposure, including risk for post-traumatic …

Genetic approaches for the study of PTSD: Advances and challenges

SB Banerjee, FG Morrison, KJ Ressler - Neuroscience letters, 2017 - Elsevier
Post-traumatic stress disorder (PTSD) is a highly debilitating stress and anxiety-related
disorder that occurs in response to specific trauma or abuse. Genetic risk factors may …