[HTML][HTML] Cytokines and chemokines: At the crossroads of cell signalling and inflammatory disease
Inflammation occurs as a result of exposure of tissues and organs to harmful stimuli such as
microbial pathogens, irritants, or toxic cellular components. The primary physical …
microbial pathogens, irritants, or toxic cellular components. The primary physical …
The interleukin (IL)-1 cytokine family–Balance between agonists and antagonists in inflammatory diseases
Abstract The interleukin (IL)-1 family of cytokines comprises 11 members, including 7 pro-
inflammatory agonists (IL-1α, IL-1β, IL-18, IL-33, IL-36α, IL-36β, IL-36γ) and 4 defined or …
inflammatory agonists (IL-1α, IL-1β, IL-18, IL-33, IL-36α, IL-36β, IL-36γ) and 4 defined or …
IL-1 family members in cancer; two sides to every story
The IL-1 family of cytokines currently comprises of seven ligands with pro-inflammatory
activity (IL-1α and IL-1β, IL-18, IL-33, IL-36α, IL-36β, IL-36γ) as well as two ligands with anti …
activity (IL-1α and IL-1β, IL-18, IL-33, IL-36α, IL-36β, IL-36γ) as well as two ligands with anti …
Immune response and inflammatory pathway of ulcerative colitis
Ulcerative colitis (UC) is an idiopathic relapsing inflammatory disease. Although the etiology
of UC remains unclear, it could be characterized by inflammation of the intestinal mucosa …
of UC remains unclear, it could be characterized by inflammation of the intestinal mucosa …
Structural basis of IL-1 family cytokine signaling
Interleukin-1 (IL-1) family cytokines are key signaling molecules in both the innate and
adaptive immune systems, mediating inflammation in response to a wide range of stimuli …
adaptive immune systems, mediating inflammation in response to a wide range of stimuli …
The family of the interleukin‐1 receptors
The extracellular forms of the IL‐1 cytokines are active through binding to specific receptors
on the surface of target cells. IL‐1 ligands bind to the extracellular portion of their ligand …
on the surface of target cells. IL‐1 ligands bind to the extracellular portion of their ligand …
Cytokines in psoriasis
J Baliwag, DH Barnes, A Johnston - Cytokine, 2015 - Elsevier
Psoriasis is a common inflammatory skin disease with an incompletely understood etiology.
The disease is characterized by red, scaly and well-demarcated skin lesions formed by the …
The disease is characterized by red, scaly and well-demarcated skin lesions formed by the …
The IL-1 family cytokines and receptors in autoimmune diseases
P Migliorini, P Italiani, F Pratesi, I Puxeddu… - Autoimmunity …, 2020 - Elsevier
The role of the cytokines and receptors of the IL-1 family in inflammation is well known.
Several cytokines of the family have a powerful inflammatory activity, with IL-1β being the …
Several cytokines of the family have a powerful inflammatory activity, with IL-1β being the …
B cells responses and cytokine production are regulated by their immune microenvironment
MI Vazquez, J Catalan-Dibene, A Zlotnik - Cytokine, 2015 - Elsevier
The adaptive immune system consists of two types of lymphocytes: T and B cells. These two
lymphocytes originate from a common precursor, yet are fundamentally different with B cells …
lymphocytes originate from a common precursor, yet are fundamentally different with B cells …
The IL-1 cytokine family and its role in inflammation and fibrosis in the lung
LA Borthwick - Seminars in immunopathology, 2016 - Springer
The IL-1 cytokine family comprises 11 members (7 ligands with agonist activity, 3 receptor
antagonists and 1 anti-inflammatory cytokine) and is recognised as a key mediator of …
antagonists and 1 anti-inflammatory cytokine) and is recognised as a key mediator of …