Photoreceptor cells and RPE contribute to the development of diabetic retinopathy

D Tonade, TS Kern - Progress in retinal and eye research, 2021 - Elsevier
Diabetic retinopathy (DR) is a leading cause of blindness. It has long been regarded as
vascular disease, but work in the past years has shown abnormalities also in the neural …

Diabetic macular ischaemia-a new therapeutic target?

CMG Cheung, A Fawzi, KYC Teo, H Fukuyama… - Progress in retinal and …, 2022 - Elsevier
Diabetic macular ischaemia (DMI) is traditionally defined and graded based on the
angiographic evidence of an enlarged and irregular foveal avascular zone. However, these …

Association between vessel density and visual acuity in patients with diabetic retinopathy and poorly controlled type 1 diabetes

B Dupas, W Minvielle, S Bonnin, A Couturier… - JAMA …, 2018 - jamanetwork.com
Importance Capillary dropout is a hallmark of diabetic retinopathy, but its role in visual loss
remains unclear. Objective To examine how macular vessel density is correlated with visual …

Adaptive optics reveals photoreceptor abnormalities in diabetic macular ischemia

PL Nesper, F Scarinci, AA Fawzi - PloS one, 2017 - journals.plos.org
Diabetic macular ischemia (DMI) is a phenotype of diabetic retinopathy (DR) associated with
chronic hypoxia of retinal tissue. The goal of this prospective observational study was to …

Adaptive optics (rtx1) high‐resolution imaging of photoreceptors and retinal arteries in patients with diabetic retinopathy

A Zaleska-Żmijewska, ZM Wawrzyniak… - Journal of diabetes …, 2019 - Wiley Online Library
Background. Diabetic retinopathy (DR) is the leading cause of impaired vision in patients
with diabetes mellitus. An adaptive optics retinal camera (rtx1™; Imagine Eyes, France) was …

Retinal sensitivity loss correlates with deep capillary plexus impairment in diabetic macular ischemia

F Scarinci, M Varano, M Parravano - Journal of Ophthalmology, 2019 - Wiley Online Library
Purpose. To assess retinal sensitivity and retinal morphologic changes of capillary
nonperfused areas in diabetic macular ischemia. Methods. Observational cross‐sectional …

In vivo assessment of associations between photoreceptors structure and macular perfusion in type 1 diabetes

P Viggiano, E Costanzo, D Giannini… - British Journal of …, 2023 - bjo.bmj.com
Purpose To explore the potential relationships between macular vascular network and
different adaptive optics (AO) metrics in patients with type 1 diabetes mellitus (DM1) with no …

Photoreceptor-based biomarkers in AOSLO retinal imaging

KM Litts, RF Cooper, JL Duncan… - … ophthalmology & visual …, 2017 - iovs.arvojournals.org
Improved understanding of the mechanisms underlying inherited retinal degenerations has
created the possibility of develo** much needed treatments for these relentless, blinding …

[HTML][HTML] Arterial hypertension and the hidden disease of the eye: diagnostic tools and therapeutic strategies

R Del Pinto, G Mulè, M Vadalà, C Carollo, S Cottone… - Nutrients, 2022 - mdpi.com
Hypertension is a major cardiovascular risk factor that is responsible for a heavy burden of
morbidity and mortality worldwide. A critical aspect of cardiovascular risk estimation in …

Retinal Photoreceptors and Microvascular Changes in Prediabetes Measured with Adaptive Optics (rtx1™): A Case‐Control Study

A Zaleska-Żmijewska, P Piątkiewicz… - Journal of diabetes …, 2017 - Wiley Online Library
Background. Patients with prediabetes are at risk for diabetes, cardiovascular events, and
microvascular complications. The rtx1 (Imagine Eyes, France) permits early detection of …