Despite the advent of sophisticated and efficient new biologics to treat inflammation in
asthma, the disease persists. Even following treatment, many patients still experience the …

Airway epithelial barrier dysfunction is frequently observed in asthma and may have
important implications. The physical barrier function of the airway epithelium is tightly …

Modern health care requires a proactive and individualized response to diseases,
combining precision diagnosis and personalized treatment. Accordingly, the approach to …

Respiratory viral infections are the most important triggers of asthma exacerbations.
Rhinovirus (RV), the common cold virus, is clearly the most prevalent pathogen constantly …

Exposure to air pollution is a major contributor to the pathogenesis of COPD worldwide.
Indeed, most recent estimates suggest that 50% of the total attributable risk of COPD may be …

Black, Latinx, and Indigenous people in the United States experience a disproportionate
burden of asthma and atopic dermatitis. The study of these disease disparities has focused …

Asthma is a complex and heterogeneous chronic inflammatory disease of the airways.
Alongside environmental factors, asthma susceptibility is strongly influenced by genetics …

Investigation of gene‐environment interactions (GxE) may provide important insights into the
gene regulatory framework in response to environmental factors of relevance for childhood …

Increase of allergic conditions has occurred at the same pace with the Great Acceleration,
which stands for the rapid growth rate of human activities upon earth from 1950s. Changes …

Allergic diseases and asthma are heterogenous chronic inflammatory conditions with
several distinct complex endotypes. Both environmental and genetic factors can influence …