Autism spectrum disorder: neuropathology and animal models

M Varghese, N Keshav, S Jacot-Descombes… - Acta …, 2017 - Springer
Autism spectrum disorder (ASD) has a major impact on the development and social
integration of affected individuals and is the most heritable of psychiatric disorders. An …

Neuroimaging in autism spectrum disorder: brain structure and function across the lifespan

C Ecker, SY Bookheimer, DGM Murphy - The Lancet Neurology, 2015 - thelancet.com
Over the past decade, in-vivo MRI studies have provided many invaluable insights into the
neural substrates underlying autism spectrum disorder (ASD), which is now known to be …

Early brain development in infants at high risk for autism spectrum disorder

HC Hazlett, H Gu, BC Munsell, SH Kim, M Styner… - Nature, 2017 - nature.com
Brain enlargement has been observed in children with autism spectrum disorder (ASD), but
the timing of this phenomenon, and the relationship between ASD and the appearance of …

Early identification of autism spectrum disorder: recommendations for practice and research

L Zwaigenbaum, ML Bauman, WL Stone… - …, 2015 - publications.aap.org
Early identification of autism spectrum disorder (ASD) is essential to ensure that children can
access specialized evidence-based interventions that can help to optimize long-term …

Altered proliferation and networks in neural cells derived from idiopathic autistic individuals

MC Marchetto, H Belinson, Y Tian, BC Freitas… - Molecular …, 2017 - nature.com
Autism spectrum disorders (ASD) are common, complex and heterogeneous
neurodevelopmental disorders. Cellular and molecular mechanisms responsible for ASD …

Pathological priming causes developmental gene network heterochronicity in autistic subject-derived neurons

ST Schafer, ACM Paquola, S Stern, D Gosselin… - Nature …, 2019 - nature.com
Autism spectrum disorder (ASD) is thought to emerge during early cortical development.
However, the exact developmental stages and associated molecular networks that prime …

Autism spectrum disorder: advances in diagnosis and evaluation

L Zwaigenbaum, M Penner - Bmj, 2018 - bmj.com
Autism spectrum disorder (ASD) has a variety of causes, and its clinical expression is
generally associated with substantial disability throughout the lifespan. Recent advances …

Patches of disorganization in the neocortex of children with autism

R Stoner, ML Chow, MP Boyle… - … England Journal of …, 2014 - Mass Medical Soc
Background Autism involves early brain overgrowth and dysfunction, which is most strongly
evident in the prefrontal cortex. As assessed on pathological analysis, an excess of neurons …

Characteristics of brains in autism spectrum disorder: structure, function and connectivity across the lifespan

S Ha, IJ Sohn, N Kim, HJ Sim… - Experimental …, 2015 - pmc.ncbi.nlm.nih.gov
Autism spectrum disorder (ASD) is a highly prevalent neurodevelopmental disorder
characterized by impaired social communication and restricted and repetitive behaviors …

Autism spectrum disorder in adults: diagnosis, management, and health services development

CM Murphy, CE Wilson, DM Robertson… - Neuropsychiatric …, 2016 - Taylor & Francis
Autism spectrum disorder (ASD) is a common neurodevelopmental disorder characterized
by pervasive difficulties since early childhood across reciprocal social communication and …