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Browning of the white adipose tissue regulation: New insights into nutritional and metabolic relevance in health and diseases
SA Machado, G Pasquarelli-do-Nascimento… - Nutrition & …, 2022 - Springer
Adipose tissues are dynamic tissues that play crucial physiological roles in maintaining
health and homeostasis. Although white adipose tissue and brown adipose tissue are …
health and homeostasis. Although white adipose tissue and brown adipose tissue are …
Sex differences in brown adipose tissue function: sex hormones, glucocorticoids, and their crosstalk
Excessive fat accumulation in the body causes overweight and obesity. To date, research
has confirmed that there are two types of adipose tissue with opposing functions: lipid …
has confirmed that there are two types of adipose tissue with opposing functions: lipid …
[HTML][HTML] Light modulates glucose metabolism by a retina-hypothalamus-brown adipose tissue axis
Public health studies indicate that artificial light is a high-risk factor for metabolic disorders.
However, the neural mechanism underlying metabolic modulation by light remains elusive …
However, the neural mechanism underlying metabolic modulation by light remains elusive …
[HTML][HTML] Altered brown fat thermoregulation and enhanced cold-induced thermogenesis in young, healthy, winter-swimming men
S Søberg, J Löfgren, FE Philipsen, M Jensen… - Cell Reports …, 2021 - cell.com
The Scandinavian winter-swimming culture combines brief dips in cold water with hot sauna
sessions, with conceivable effects on body temperature. We study thermogenic brown …
sessions, with conceivable effects on body temperature. We study thermogenic brown …
Seasonal light hours modulate peripheral clocks and energy metabolism in mice
Except for latitudes close to the equator, seasonal variation in light hours can change
dramatically between summer and winter. Yet investigations into the interplay between …
dramatically between summer and winter. Yet investigations into the interplay between …
Lipolysis regulates major transcriptional programs in brown adipocytes
LK Markussen, EA Rondini, OS Johansen… - Nature …, 2022 - nature.com
Abstract β-Adrenergic signaling is a core regulator of brown adipocyte function stimulating
both lipolysis and transcription of thermogenic genes, thereby expanding the capacity for …
both lipolysis and transcription of thermogenic genes, thereby expanding the capacity for …
NAMPT-dependent NAD+ biosynthesis controls circadian metabolism in a tissue-specific manner
Molecular clocks in the periphery coordinate tissue-specific daily biorhythms by integrating
input from the hypothalamic master clock and intracellular metabolic signals. One such key …
input from the hypothalamic master clock and intracellular metabolic signals. One such key …
The circadian clock and metabolic homeostasis: entangled networks
The circadian clock exerts an important role in systemic homeostasis as it acts a keeper of
time for the organism. The synchrony between the daily challenges imposed by the …
time for the organism. The synchrony between the daily challenges imposed by the …
Time-restricted feeding attenuates hypercholesterolaemia and atherosclerosis development during circadian disturbance in APOE∗ 3-Leiden. CETP mice
Background Circadian disturbance (CD) is the consequence of a mismatch between
endogenous circadian rhythms, behaviour, and/or environmental cycles, and frequently …
endogenous circadian rhythms, behaviour, and/or environmental cycles, and frequently …
Mechanisms in endocrinology: local and systemic effects of glucocorticoids on metabolism: new lessons from animal models
Glucocorticoids regulate a remarkable variety of essential functions, including development,
immunomodulation, maintenance of circadian rhythm and the response to stress …
immunomodulation, maintenance of circadian rhythm and the response to stress …