Recognition in the domain of molecular chirality: from noncovalent interactions to separation of enantiomers

P Peluso, B Chankvetadze - Chemical Reviews, 2022 - ACS Publications
It is not a coincidence that both chirality and noncovalent interactions are ubiquitous in
nature and synthetic molecular systems. Noncovalent interactivity between chiral molecules …

Recent Advances in Chiral Selectors Immobilization and Chiral Mobile Phase Additives in Liquid Chromatographic Enantio-separations; A Review

AE Ibrahim, NA El Gohary, D Aboushady… - … of Chromatography A, 2023 - Elsevier
For decades now, the separation of chiral enantiomers of drugs has been gaining the
interest and attention of researchers. In 1991, the first guidelines for development of chiral …

Interrogating the CISS effect in chiral and paramagnetic organic radicals: the impact of the molecular spin over the total spin polarization

JA De Sousa, P Mayorga-Burrezo… - Journal of Materials …, 2024 - pubs.rsc.org
Continuous research on new chiral molecular materials brings new exciting properties to the
field of molecular electronics. The discovery of the chirality-induced spin selectivity (CISS) …

[HTML][HTML] Unravelling dispersion forces in liquid-phase enantioseparation. Part I: Impact of ferrocenyl versus phenyl groups

B Sechi, A Dessì, R Dallocchio, N Tsetskhladze… - Analytica Chimica …, 2023 - Elsevier
Background Highly ordered chiral secondary structures as well as multiple (tunable)
recognition sites are the keys to success of polysaccharide carbamate-based chiral …

[HTML][HTML] Chiral separation of oxazolidinone analogues by liquid chromatography on polysaccharide stationary phases using polar organic mode

M Dobó, M Foroughbakhshfasaei, P Horváth… - … of Chromatography A, 2022 - Elsevier
The enantioseparation of four oxazolidinone and one biosimilar thiazolidine derivatives was
performed on seven different polysaccharide-type chiral stationary phases (Lux Amylose-1 …

Enantioseparation of 5, 5′-dibromo-2, 2′-dichloro-3-selanyl-4, 4′-bipyridines on polysaccharide-based chiral stationary phases: Exploring chalcogen bonds in …

P Peluso, A Dessì, R Dallocchio, B Sechi, C Gatti… - Molecules, 2021 - mdpi.com
The chalcogen bond (ChB) is a noncovalent interaction based on electrophilic features of
regions of electron charge density depletion (σ-holes) located on bound atoms of group VI …

Unravelling functions of halogen substituents in the enantioseparation of halogenated planar chiral ferrocenes on polysaccharide-based chiral stationary phases …

B Sechi, A Dessì, C Gatti, R Dallocchio… - … of Chromatography A, 2022 - Elsevier
Planar chiral halogenated ferrocenes have come in useful as synthetic intermediates over
the years, allowing for the preparation of functionalized derivatives for catalysis, material …

[HTML][HTML] Enantioseparation of new axially chiral carboxylic acids on polysaccharide-based chiral stationary phases under normal phase elution conditions

B Sechi, V Mamane, R Dallocchio, A Dessì… - … of Pharmaceutical and …, 2023 - Elsevier
In the last decade, the availability of new and versatile synthetic strategies for the
preparation of substituted 4, 4'-bipyridyl derivatives based on chemo-and regioselective …

[HTML][HTML] Exploring interaction modes between polysaccharide-based selectors and biologically active 4, 4′-bipyridines by experimental and computational analysis

R Dallocchio, A Dessì, B Sechi, B Chankvetadze… - Journal of …, 2022 - Elsevier
In the last few years, chiral 4, 4′-bipyridine derivatives have been developed for different
applications in catalysis, enantioseparation science, supramolecular and theoretical …

Comparative enantioseparation of planar chiral ferrocenes on polysaccharide‐based chiral stationary phases

A Dessì, B Sechi, R Dallocchio, B Chankvetadze… - Chirality, 2022 - Wiley Online Library
Planar chiral ferrocenes are well‐known compounds that have attracted interest for
application in synthesis, catalysis, material science, and medicinal chemistry for several …