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Disease manifestations and pathogenic mechanisms of group A Streptococcus
Streptococcus pyogenes, also known as group A Streptococcus (GAS), causes mild human
infections such as pharyngitis and impetigo and serious infections such as necrotizing …
infections such as pharyngitis and impetigo and serious infections such as necrotizing …
Recurrent group A Streptococcus tonsillitis is an immunosusceptibility disease involving antibody deficiency and aberrant TFH cells
JM Dan, C Havenar-Daughton, K Kendric… - Science translational …, 2019 - science.org
“Strep throat” is highly prevalent among children, yet it is unknown why only some children
develop recurrent tonsillitis (RT), a common indication for tonsillectomy. To gain insights into …
develop recurrent tonsillitis (RT), a common indication for tonsillectomy. To gain insights into …
Human disease isolates of serotype M4 and M22 group A Streptococcus lack genes required for hyaluronic acid capsule biosynthesis
Group A streptococcus (GAS) causes human pharyngitis and invasive infections and
frequently colonizes individuals asymptomatically. Many lines of evidence generated over …
frequently colonizes individuals asymptomatically. Many lines of evidence generated over …
The fall and rise of Group A Streptococcus diseases
Streptococcus pyogenes (or Group A Streptococcus, GAS) is a Gram-positive human
pathogen responsible for a diverse array of superficial, invasive and immune-related …
pathogen responsible for a diverse array of superficial, invasive and immune-related …
Emergence of a New Highly Successful Acapsular Group A Streptococcus Clade of Genotype emm89 in the United Kingdom
ABSTRACT Group A Streptococcus (GAS) genotype emm 89 is increasingly recognized as a
leading cause of disease worldwide, yet factors that underlie the success of this emm type …
leading cause of disease worldwide, yet factors that underlie the success of this emm type …
A molecular trigger for intercontinental epidemics of group A Streptococcus
The identification of the molecular events responsible for strain emergence, enhanced
virulence, and epidemicity has been a long-pursued goal in infectious diseases research. A …
virulence, and epidemicity has been a long-pursued goal in infectious diseases research. A …
Integrated analysis of population genomics, transcriptomics and virulence provides novel insights into Streptococcus pyogenes pathogenesis
Streptococcus pyogenes causes 700 million human infections annually worldwide, yet,
despite a century of intensive effort, there is no licensed vaccine against this bacterium …
despite a century of intensive effort, there is no licensed vaccine against this bacterium …
Trading Capsule for Increased Cytotoxin Production: Contribution to Virulence of a Newly Emerged Clade of emm89 Streptococcus pyogenes
Strains of emm89 Streptococcus pyogenes have become one of the major causes of
invasive infections worldwide in the last 10 years. We recently sequenced the genome of …
invasive infections worldwide in the last 10 years. We recently sequenced the genome of …
Epidemiology of invasive group A streptococcal infections in Norway 2010–2014: a retrospective cohort study
U Naseer, M Steinbakk, H Blystad… - European Journal Of …, 2016 - Springer
Streptococcus pyogenes or group A streptococcus (GAS) causes mild to severe infections in
humans. GAS genotype emm1 is the leading cause of invasive disease worldwide. In the …
humans. GAS genotype emm1 is the leading cause of invasive disease worldwide. In the …
Role of operative or interventional radiology-guided cultures for osteomyelitis
METHODS: A retrospective review of cases of AHO was performed from 2011 to 2014.
Patients with chronic disease, orthopedic hardware, puncture wounds, or an infected …
Patients with chronic disease, orthopedic hardware, puncture wounds, or an infected …