Cerebral oxygen extraction fraction MRI: Techniques and applications

D Jiang, H Lu - Magnetic resonance in medicine, 2022 - Wiley Online Library
The human brain constitutes 2% of the body's total mass but uses 20% of the oxygen. The
rate of the brain's oxygen utilization can be derived from a knowledge of cerebral blood flow …

Blood oxygenation level‐dependent (BOLD)‐based techniques for the quantification of brain hemodynamic and metabolic properties–theoretical models and …

DA Yablonskiy, AL Sukstanskii, X He - NMR in Biomedicine, 2013 - Wiley Online Library
The quantitative evaluation of brain hemodynamics and metabolism, particularly the
relationship between brain function and oxygen utilization, is important for the …

Quantitative oxygenation venography from MRI phase

AP Fan, B Bilgic, L Gagnon, T Witzel… - Magnetic resonance …, 2014 - Wiley Online Library
Purpose To demonstrate acquisition and processing methods for quantitative oxygenation
venograms that map in vivo oxygen saturation (SvO2) along cerebral venous vasculature …

Quantitative map** of cerebral metabolic rate of oxygen (CMRO2) using quantitative susceptibility map** (QSM)

J Zhang, T Liu, A Gupta, P Spincemaille… - Magnetic resonance …, 2015 - Wiley Online Library
Purpose To quantitatively map cerebral metabolic rate of oxygen () and oxygen extraction
fraction () in human brains using quantitative susceptibility map** (QSM) and arterial spin …

MRI-based methods for quantification of the cerebral metabolic rate of oxygen

ZB Rodgers, JA Detre… - Journal of Cerebral Blood …, 2016 - journals.sagepub.com
The brain depends almost entirely on oxidative metabolism to meet its significant energy
requirements. As such, the cerebral metabolic rate of oxygen (CMRO2) represents a key …

Cerebral metabolic rate of oxygen (CMRO2) map** with hyperventilation challenge using quantitative susceptibility map** (QSM)

J Zhang, D Zhou, TD Nguyen… - Magnetic resonance …, 2017 - Wiley Online Library
Purpose Our objective was to demonstrate the feasibility of using hyperventilation as an
efficient vasoconstrictive challenge and prior knowledge as denoising constraints for …

Susceptibility‐based time‐resolved whole‐organ and regional tissue oximetry

FW Wehrli, AP Fan, ZB Rodgers… - NMR in …, 2017 - Wiley Online Library
The magnetism of hemoglobin–being paramagnetic in its deoxy and diamagnetic in its oxy
state–offers unique opportunities to probe oxygen metabolism in blood and tissues. The …

High temporal resolution MRI quantification of global cerebral metabolic rate of oxygen consumption in response to apneic challenge

ZB Rodgers, V Jain, EK Englund… - Journal of Cerebral …, 2013 - journals.sagepub.com
We present a technique for quantifying global cerebral metabolic rate of oxygen
consumption (CMRO2) in absolute physiologic units at 3-second temporal resolution and …

Quantitative susceptibility map**‐based cerebral metabolic rate of oxygen map** with minimum local variance

J Zhang, J Cho, D Zhou, TD Nguyen… - Magnetic resonance …, 2018 - Wiley Online Library
Purpose The objective of this study was to demonstrate the feasibility of a cerebral metabolic
rate of oxygen (CMRO2) map** method based on its minimum local variance (MLV) …

[HTML][HTML] Combined measurement of perfusion, venous oxygen saturation, and skeletal muscle T2* during reactive hyperemia in the leg

EK Englund, MC Langham, C Li, ZB Rodgers… - Journal of …, 2013 - Elsevier
Background The function of the peripheral microvascular may be interrogated by measuring
perfusion, tissue oxygen concentration, or venous oxygen saturation (SvO 2) recovery …