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Biodemography of human ageing
JW Vaupel - Nature, 2010 - nature.com
Human senescence has been delayed by a decade. This finding, documented in 1994 and
bolstered since, is a fundamental discovery about the biology of human ageing, and one …
bolstered since, is a fundamental discovery about the biology of human ageing, and one …
Physiological geroscience: targeting function to increase healthspan and achieve optimal longevity
Most nations of the world are undergoing rapid and dramatic population ageing, which
presents great socio‐economic challenges, as well as opportunities, for individuals, families …
presents great socio‐economic challenges, as well as opportunities, for individuals, families …
[LIBRO][B] Measuring well-being: Interdisciplinary perspectives from the social sciences and the humanities
This edited volume focuses on both conceptual and practical challenges in measuring well-
being. Leveraging insights across diverse disciplines, including psychology, economics …
being. Leveraging insights across diverse disciplines, including psychology, economics …
Differences in life expectancy due to race and educational differences are widening, and many may not catch up
It has long been known that despite well-documented improvements in longevity for most
Americans, alarming disparities persist among racial groups and between the well-educated …
Americans, alarming disparities persist among racial groups and between the well-educated …
Healthy aging and muscle function are positively associated with NAD+ abundance in humans
Skeletal muscle is greatly affected by aging, resulting in a loss of metabolic and physical
function. However, the underlying molecular processes and how (lack of) physical activity is …
function. However, the underlying molecular processes and how (lack of) physical activity is …
Healthy aging diets other than the Mediterranean: a focus on the Okinawan diet
DC Willcox, G Scapagnini, BJ Willcox - Mechanisms of ageing and …, 2014 - Elsevier
The traditional diet in Okinawa is anchored by root vegetables (principally sweet potatoes),
green and yellow vegetables, soybean-based foods, and medicinal plants. Marine foods …
green and yellow vegetables, soybean-based foods, and medicinal plants. Marine foods …
Substantial health and economic returns from delayed aging may warrant a new focus for medical research
Recent scientific advances suggest that slowing the aging process (senescence) is now a
realistic goal. Yet most medical research remains focused on combating individual diseases …
realistic goal. Yet most medical research remains focused on combating individual diseases …
Human serum metabolic profiles are age dependent
Understanding the complexity of aging is of utmost importance. This can now be addressed
by the novel and powerful approach of metabolomics. However, to date, only a few …
by the novel and powerful approach of metabolomics. However, to date, only a few …
Overexpression of catalase targeted to mitochondria attenuates murine cardiac aging
Background—Age is a major risk for cardiovascular diseases. Although mitochondrial
reactive oxygen species have been proposed as one of the causes of aging, their role in …
reactive oxygen species have been proposed as one of the causes of aging, their role in …
Human aging is characterized by focused changes in gene expression and deregulation of alternative splicing
Aging is a major risk factor for chronic disease in the human population, but there are little
human data on gene expression alterations that accompany the process. We examined …
human data on gene expression alterations that accompany the process. We examined …