Phytochemical and Therapeutic Potential of Citrus grandis (L.) Osbeck: A Review

RJ Anmol, S Marium, FT Hiew… - Journal of evidence …, 2021 - journals.sagepub.com
Citrus grandis or Citrus maxima, widely recognized as Pomelo is widely cultivated in many
countries because of their large amounts of functional, nutraceutical and biological activities …

Anticoronavirus and immunomodulatory phenolic compounds: Opportunities and pharmacotherapeutic perspectives

NN Dejani, HA Elshabrawy, CSM Bezerra Filho… - Biomolecules, 2021 - mdpi.com
In 2019, COVID-19 emerged as a severe respiratory disease that is caused by the novel
coronavirus, Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2). The …

Rhoifolin loaded in PLGA nanoparticles alleviates oxidative stress and inflammation in vitro and in vivo

E Al-Shalabi, S Abusulieh, AM Hammad… - Biomaterials …, 2022 - pubs.rsc.org
Rhoifolin (ROF) is a bioactive plant flavonoid with potent antioxidant and anti-inflammatory
activity. However, no delivery system has yet been developed for ROF to overcome its …

Wound-Healing Potential of Rhoifolin-Rich Fraction Isolated from Sanguisorba officinalis Roots Supported by Enhancing Re-Epithelization, Angiogenesis, Anti …

WA Negm, AH El-Kadem, E Elekhnawy, NGM Attallah… - Pharmaceuticals, 2022 - mdpi.com
A wound is a complicated bioprocess resulting in significant tissue damage, which is
worsened by a secondary bacterial infection, commonly Pseudomonas aeruginosa and …

Melatonin-Derived Carbon Dots with Free Radical Scavenging Property for Effective Periodontitis Treatment via the Nrf2/HO-1 Pathway

X **n, J Liu, X Liu, Y **n, Y Hou, X **ang, Y Deng… - ACS …, 2024 - ACS Publications
Periodontitis is a chronic inflammatory disease closely associated with reactive oxygen
species (ROS) involvement. Eliminating ROS to control the periodontal microenvironment …

Physicochemical evaluation, structural characterization, in vitro and in vivo bioactivities of water-soluble polysaccharides from Luobuma (Apocynum L.) tea

AS Abubakar, B Ahmad, N Ahmad, L Liu, B Liu, Y Qu… - Food Chemistry, 2024 - Elsevier
Luobuma tea is made from the leaves of Apocynum hendersonii (Bt) and A. venetum (Ht)
and has been used for a very long time in China and Japan as herbal tea. This study …

Evaluation of the anti-inflammatory effects of PI3Kδ/γ inhibitors for treating acute lung injury

W **ong, L Jia, Y Cai, Y Chen, M Gao, J **, J Zhu - Immunobiology, 2023 - Elsevier
Abstract Phosphatidylinositol 3-kinase delta (PI3Kδ) and gamma (PI3Kγ) are predominantly
located in immune and hematopoietic cells. It is well-established that PI3Kδ/γ plays …

Hepatoprotective effect of silver nanoparticles at two different particle sizes: Comparative study with and without silymarin

MA Elfaky, A Sirwi, SH Ismail, HH Awad… - Current Issues in …, 2022 - mdpi.com
Silver nanoparticles have been used for numerous therapeutic purposes because of their
increased biodegradability and bioavailability, yet their toxicity remains questionable as they …

Rhoifolin Alleviates Alcoholic Liver Disease In Vivo and In Vitro via Inhibition of the TLR4/NF-κB Signaling Pathway

B Mai, L Han, J Zhong, J Shu, Z Cao, J Fang… - Frontiers in …, 2022 - frontiersin.org
Background: Alcoholic liver disease (ALD) is a common chronic liver disorder worldwide,
which is detrimental to human health. A preliminary study showed that the total flavonoids …

Painong-San extract alleviates dextran sulfate sodium-induced colitis in mice by modulating gut microbiota, restoring intestinal barrier function and attenuating TLR4 …

K Wang, J Guo, X Chang, S Gui - Journal of Pharmaceutical and Biomedical …, 2022 - Elsevier
Highlights•The mechanisms of Painong-San extract (PNS) related to gut microbiota in
treating ulcerative colitis were revealed.•125 active compounds were identified from PNS by …