Monitoring the emergence and re-emergence of viral diseases with the goal of containing
the spread of viral agents requires both adequate preparedness and quick response …

Although viruses comprise the most abundant genetic material in the biosphere, to date only
several thousand virus species have been formally defined. Such a limited perspective on …

Pangolins are endangered animals in urgent need of protection. Identifying and cataloguing
the viruses carried by pangolins is a logical approach to evaluate the range of potential …

The progress of science is punctuated by the advent of revolutionary technologies that
provide new ways and scales to formulate scientific questions and advance knowledge …

The frequent interactions of rodents with humans make them a common source of zoonotic
infections. To obtain an initial unbiased measure of the viral diversity in the enteric tract of …

Low-cost DNA sequencing technologies have expanded the role for direct nucleic acid
sequencing in the analysis of genomes, transcriptomes, and the metagenomes of whole …

Novel DNA sequencing techniques, referred to as “next-generation” sequencing (NGS),
provide high speed and throughput that can produce an enormous volume of sequences …

Highlights•Pathogen discovery is critically important to infectious diseases and public
health.•Nearly all new outbreaks are caused by the emergence of novel viruses.•Genomic …

It is hard to overemphasize the role that metagenomics has had on our recent understanding
of RNA virus diversity. Metagenomics in the 21st century has brought with it an explosion in …

Cardiovascular diseases (CVDs) are the leading cause of death worldwide. An expanding
body of evidence supports the role of human microbiome in the establishment of CVDs and …