Perivascular spaces in the brain: anatomy, physiology and pathology
Perivascular spaces include a variety of passageways around arterioles, capillaries and
venules in the brain, along which a range of substances can move. Although perivascular …
venules in the brain, along which a range of substances can move. Although perivascular …
Inflammation and cerebral small vessel disease: a systematic review
Inflammation is increasingly implicated as a risk factor for dementia, stroke, and small vessel
disease (SVD). However, the underlying mechanisms and causative pathways remain …
disease (SVD). However, the underlying mechanisms and causative pathways remain …
[HTML][HTML] Emerging concepts in vascular dementia: a review
SC Bir, MW Khan, V Javalkar, EG Toledo… - Journal of Stroke and …, 2021 - Elsevier
Abstract Objective Vascular dementia (VaD) is the second most common cause of dementia
and a major health concern worldwide. A comprehensive review on VaD is warranted for …
and a major health concern worldwide. A comprehensive review on VaD is warranted for …
Association of dilated perivascular spaces with cognitive decline and incident dementia
Objective To determine whether severe perivascular space (PVS) dilation is associated with
longitudinal cognitive decline and incident dementia over 4 and 8 years, respectively, we …
longitudinal cognitive decline and incident dementia over 4 and 8 years, respectively, we …
[HTML][HTML] Cerebral small vessel disease alters neurovascular unit regulation of microcirculation integrity involved in vascular cognitive impairment
Q Yang, X Wei, B Deng, Z Chang, D **, Y Huang… - Neurobiology of …, 2022 - Elsevier
Cerebral small vessel disease (CSVD) is a generic term used for intracranial vascular
disorders caused by the structural changes of cerebral microvessels, including the small …
disorders caused by the structural changes of cerebral microvessels, including the small …
Association of enlarged perivascular spaces and measures of small vessel and Alzheimer disease
EC Gertje, D van Westen, C Panizo… - Neurology, 2021 - AAN Enterprises
Objective To investigate the relationship between enlarged perivascular spaces (EPVS) and
measures of Alzheimer disease (AD), small vessel disease (SVD), cognition, vascular risk …
measures of Alzheimer disease (AD), small vessel disease (SVD), cognition, vascular risk …
[HTML][HTML] Imaging perivascular space structure and function using brain MRI
In this article, we provide an overview of current neuroimaging methods for studying
perivascular spaces (PVS) in humans using brain MRI. In recent years, an increasing …
perivascular spaces (PVS) in humans using brain MRI. In recent years, an increasing …
Physiology and clinical relevance of enlarged perivascular spaces in the aging brain
Perivascular spaces (PVS) are fluid-filled compartments that are part of the cerebral blood
vessel wall and represent the conduit for fluid transport in and out of the brain. PVS are …
vessel wall and represent the conduit for fluid transport in and out of the brain. PVS are …
The glymphatic system's role in traumatic brain injury-related neurodegeneration
In at least some individuals who suffer a traumatic brain injury (TBI), there exists a risk of
future neurodegenerative illness. This review focuses on the association between the brain …
future neurodegenerative illness. This review focuses on the association between the brain …
Volumetric distribution of perivascular space in relation to mild cognitive impairment
Vascular contributions to early cognitive decline are increasingly recognized, prompting
further investigation into the nature of related changes in perivascular spaces (PVS). Using …
further investigation into the nature of related changes in perivascular spaces (PVS). Using …