Publication guidelines for human heart rate and heart rate variability studies in psychophysiology—Part 1: Physiological underpinnings and foundations of …
Abstract This Committee Report provides methodological, interpretive, and reporting
guidance for researchers who use measures of heart rate (HR) and heart rate variability …
guidance for researchers who use measures of heart rate (HR) and heart rate variability …
Neurohumoral control of sinoatrial node activity and heart rate: insight from experimental models and findings from humans
The sinoatrial node is perhaps one of the most important tissues in the entire body: it is the
natural pacemaker of the heart, making it responsible for initiating each-and-every normal …
natural pacemaker of the heart, making it responsible for initiating each-and-every normal …
Lipopolysaccharide-induced sepsis impairs M2R-GIRK signaling in the mouse sinoatrial node
N Shrestha, K Zorn-Pauly, P Mesirca… - Proceedings of the …, 2023 - National Acad Sciences
Sepsis has emerged as a global health burden associated with multiple organ dysfunction
and 20% mortality rate in patients. Numerous clinical studies over the past two decades …
and 20% mortality rate in patients. Numerous clinical studies over the past two decades …
Paradigm shift: new concepts for HCN4 function in cardiac pacemaking
Hyperpolarization-activated cyclic nucleotide–gated (HCN) channels are the molecular
correlate of the If current and are critically involved in controlling neuronal excitability and …
correlate of the If current and are critically involved in controlling neuronal excitability and …
[HTML][HTML] Beyond pacemaking: HCN channels in sinoatrial node function
Hyperpolarization-activated cyclic nucleotide-gated (HCN) channels are key proteins
involved in the initiation and regulation of the heartbeat. Pacemaker cells within the …
involved in the initiation and regulation of the heartbeat. Pacemaker cells within the …
Genetics of sinoatrial node function and heart rate disorders
The sinoatrial node (SAN) is the primary pacemaker of the mammalian heart, initiating its
electrical activation and ensuring that the heart's functional cardiac output meets …
electrical activation and ensuring that the heart's functional cardiac output meets …
Geomagnetic disturbances driven by solar activity enhance total and cardiovascular mortality risk in 263 US cities
Background Short-term geomagnetic disturbances (GMD) driven by the quasi-periodic 11-
year cycle of solar activity have been linked to a broad range of adverse health effects …
year cycle of solar activity have been linked to a broad range of adverse health effects …
Structural and electrical remodeling of the sinoatrial node in diabetes: new dimensions and perspectives
The sinoatrial node (SAN) is composed of highly specialized cells that mandate the
spontaneous beating of the heart through self-generation of an action potential (AP). Despite …
spontaneous beating of the heart through self-generation of an action potential (AP). Despite …
Speeding up the heart? Traditional and new perspectives on HCN4 function
The sinoatrial node (SAN) is the primary pacemaker of the heart and is responsible for
generating the intrinsic heartbeat. Within the SAN, spontaneously active pacemaker cells …
generating the intrinsic heartbeat. Within the SAN, spontaneously active pacemaker cells …
A multiscale predictive digital twin for neurocardiac modulation
PC Yang, A Rose, KR DeMarco… - The Journal of …, 2023 - Wiley Online Library
Cardiac function is tightly regulated by the autonomic nervous system (ANS). Activation of
the sympathetic nervous system increases cardiac output by increasing heart rate and stroke …
the sympathetic nervous system increases cardiac output by increasing heart rate and stroke …