The field of structure-based drug design is a rapidly growing area in which many successes
have occurred in recent years. The explosion of genomic, proteomic, and structural …

During the 50 years of NMR, the technology has renewed itself again and again although
the basic physical principles remain the same. As technical advances and novel materials …

Automated methods for protein structure determination by NMR have increasingly gained
acceptance and are now widely used for the automated assignment of distance restraints …

Progress in the structural biology of proteins comes from both experimental and theoretical
efforts. Computational methods are capable of delivering fast structural information, ranging …

This article formulates the multidimensional nuclear Overhauser effect spectroscopy
(NOESY) interpretation problem using graph theory and presents a novel, bottom‐up …

Around half of all protein structures solved nowadays using solution-state nuclear magnetic
resonance (NMR) spectroscopy have been because of automated data analysis. The …

A general-purpose Monte Carlo assignment program has been developed to aid in the
assignment of NMR resonances from proteins. By virtue of its flexible data requirements the …

The major challenge for post-genomic research is to functionally assign and validate a large
number of novel target genes and their corresponding proteins. Functional genomics …

We describe a computational approach to sequential resonance assignment in solid state
NMR studies of uniformly 15N, 13C-labeled proteins with magic-angle spinning. As input …

We have derived a quartic equation for computing the direction of an internuclear vector
from residual dipolar couplings (RDCs) measured in two aligning media, and two simple …