Hydrazinecarboxamides: comprehensive review of their anticancer, anticonvulsive, anti-inflammatory, enzyme inhibition, antioxidant and other activities
M Krátký, NH Houngbedji, J Vinšová - European Journal of Medicinal …, 2024 - Elsevier
This review comprehensively summarizes recent advances in the field of
hydrazinecarboxamide (semicarbazide) derivatives, highlighting their significant therapeutic …
hydrazinecarboxamide (semicarbazide) derivatives, highlighting their significant therapeutic …
Synthetic transformations and biological screening of benzoxazole derivatives: A review
The presence of benzoxazole moiety in most of the heterocyclic compounds is well reported.
The present literature review mainly highlights the novel synthetic transformation and …
The present literature review mainly highlights the novel synthetic transformation and …
Design, synthesis and QSAR study of certain isatin-pyridine hybrids as potential anti-proliferative agents
A hybrid pharmacophore approach was adopted to design and synthesize new series of
isatin–pyridine hybrids. All the newly prepared hybrids (5a–o, 8 and 11a–d) were in vitro …
isatin–pyridine hybrids. All the newly prepared hybrids (5a–o, 8 and 11a–d) were in vitro …
Design, synthesis, mechanistic and histopathological studies of small-molecules of novel indole-2-carboxamides and pyrazino [1, 2-a] indol-1 (2H)-ones as potential …
BGM Youssif, MH Abdelrahman… - European Journal of …, 2018 - Elsevier
A series of novel compounds carrying pyrazino [1, 2-a] indol-1 (2H)-one scaffold (5a-g) and
their reaction intermediates, indole-2-carboxamides,(3a-g) were synthesized and evaluated …
their reaction intermediates, indole-2-carboxamides,(3a-g) were synthesized and evaluated …
Preparation, structure elucidation, and antioxidant activity of new bis (thiosemicarbazone) derivatives
H Yakan - Turkish Journal of Chemistry, 2020 - journals.tubitak.gov.tr
Schiff-base-bearing new bis (thiosemicarbazone) derivatives were prepared from
terephthalaldehyde and various thiosemicarbazides. FT--IR, $^{\, 1} $ H NMR, $^{13} $ C …
terephthalaldehyde and various thiosemicarbazides. FT--IR, $^{\, 1} $ H NMR, $^{13} $ C …
Mechanistic insight and structure activity relationship of isatin-based derivatives in development of anti-breast cancer agents
Breast cancer is most common in women and most difficult to manage that causes highest
mortality and morbidity among all diseases and posing significant threat to mankind as well …
mortality and morbidity among all diseases and posing significant threat to mankind as well …
Current scenario of 1, 3-oxazole derivatives for anticancer activity
X Yan, J Wen, L Zhou, L Fan… - Current Topics in …, 2020 - ingentaconnect.com
Cancer, which has been cursed for human beings for long time is considered as one of the
leading causes of morbidity and mortality across the world. In spite of different types of …
leading causes of morbidity and mortality across the world. In spite of different types of …
Synthesis, characterization, quantum chemical calculations and antioxidant activity of new bis-isatin carbohydrazone and thiocarbohydrazone derivatives
Bis (5-chloro-2-oxoindolin-3-ylidene) thiocarbohydrazone (3), 1, 5-Bis (5-metoxy-2-
oxoindolin-3-ylidene) thiocarbohydrazone (4), 1, 5-Bis (5-metoxy-2-oxoindolin-3-ylidene) …
oxoindolin-3-ylidene) thiocarbohydrazone (4), 1, 5-Bis (5-metoxy-2-oxoindolin-3-ylidene) …
Isatin-benzoazine molecular hybrids as potential antiproliferative agents: synthesis and in vitro pharmacological profiling
In continuation of our endeavor with respect to the development of potent and effective isatin-
based anticancer agents, we adopted the molecular hybridization approach to design and …
based anticancer agents, we adopted the molecular hybridization approach to design and …
Recent advances in the development of pharmacologically active compounds that contain a benzoxazole scaffold
In recent years, the emergence of biologically active compounds that contain a heterocyclic
ring has gained a great deal of attention among medicinal chemists. Among these …
ring has gained a great deal of attention among medicinal chemists. Among these …