Fibrinolysis and the control of blood coagulation

JC Chapin, KA Hajjar - Blood reviews, 2015 - Elsevier
Fibrin plays an essential role in hemostasis as both the primary product of the coagulation
cascade and the ultimate substrate for fibrinolysis. Fibrinolysis efficiency is greatly …

Protease inhibitors in plants: genes for improving defences against insects and pathogens.

CA Ryan - 1990 - cabidigitallibrary.org
Selected current and past research relevant to the roles of proteinase inhibitors in plant
protection is reviewed with a brief introduction to families of plant proteinase inhibitors …

Free radicals, oxidative stress, and antioxidants in human health and disease

OI Aruoma - Journal of the American oil chemists' society, 1998 - Wiley Online Library
Free radicals and other reactive oxygen species (ROS) are constantly formed in the human
body. Free‐radical mechanisms have been implicated in the pathology of several human …

[BOOK][B] The organic chemistry of drug design and drug action

RB Silverman, MW Holladay - 2014 - books.google.com
The Organic Chemistry of Drug Design and Drug Action, Third Edition, represents a unique
approach to medicinal chemistry based on physical organic chemical principles and …

Biomaterials and advanced technologies for hemostatic management of bleeding

DSA Hickman, CL Pawlowski, UDS Sekhon… - Advanced …, 2018 - Wiley Online Library
Bleeding complications arising from trauma, surgery, and as congenital, disease‐
associated, or drug‐induced blood disorders can cause significant morbidities and …

Plasminogen activators, tissue degradation, and cancer

K Danø, PA Andreasen, J Grøndahl-Hansen… - Advances in cancer …, 1985 - Elsevier
Publisher Summary This chapter discusses the role of plasminogen activators in various
biological processes. In specific, it describes two types of plasminogen activators—namely …

Serpin structure, mechanism, and function

PGW Gettins - Chemical reviews, 2002 - ACS Publications
Serpins are a superfamily of proteins, whose membership is based on the presence of a
single common core domain consisting of three β-sheets and 8-9 R-helices, and with a set of …

Neutrophils: molecules, functions and pathophysiological aspects

V Witko-Sarsat, P Rieu, B Descamps-Latscha… - Laboratory …, 2000 - nature.com
CONCLUSION The notion that inflammation is the net resultant of pro and contra
inflammatory pathways (Fauve, 1980) is well illustrated by the dual role of neutrophils which …

Molecular mechanisms of NET formation and degradation revealed by intravital imaging in the liver vasculature

E Kolaczkowska, CN Jenne, BGJ Surewaard… - Nature …, 2015 - nature.com
Neutrophil extracellular traps (NETs) composed of DNA decorated with histones and
proteases trap and kill bacteria but also injure host tissue. Here we show that during a …

[HTML][HTML] Prevention strategies of postoperative adhesion in soft tissues by applying biomaterials: Based on the mechanisms of occurrence and development of …

J Liao, X Li, Y Fan - Bioactive Materials, 2023 - Elsevier
Postoperative adhesion (POA) widely occurs in soft tissues and usually leads to chronic
pain, dysfunction of adjacent organs and some acute complications, seriously reducing …