Role of the gut microbiota in anticancer therapy: from molecular mechanisms to clinical applications

LY Zhao, JX Mei, G Yu, L Lei, WH Zhang… - … and Targeted Therapy, 2023 - nature.com
In the past period, due to the rapid development of next-generation sequencing technology,
accumulating evidence has clarified the complex role of the human microbiota in the …

Natural products as reservoirs of novel therapeutic agents

S Mushtaq, BH Abbasi, B Uzair, R Abbasi - EXCLI journal, 2018 - pmc.ncbi.nlm.nih.gov
Since ancient times, natural products from plants, animals, microbial and marine sources
have been exploited for treatment of several diseases. The knowledge of our ancestors is …

Anticancer Agents

P Sharma, SK Tiwari - … in Therapeutics: Volume 1: Applications in …, 2020 - books.google.com
Cancer is one of the momentous causes of death worldwide despite the availability of
advance detection and treatment methods. The present chemotherapeutic treatments are …

[HTML][HTML] Anticancer activity of bacterial proteins and peptides

TM Karpiński, A Adamczak - Pharmaceutics, 2018 - mdpi.com
Despite much progress in the diagnosis and treatment of cancer, tumour diseases constitute
one of the main reasons of deaths worldwide. The side effects of chemotherapy and drug …

Pseudomonas aeruginosa Cytotoxins: Mechanisms of Cytotoxicity and Impact on Inflammatory Responses

SJ Wood, JW Goldufsky, MY Seu, AH Dorafshar… - Cells, 2023 - mdpi.com
Pseudomonas aeruginosa is one of the most virulent opportunistic Gram-negative bacterial
pathogens in humans. It causes many acute and chronic infections with morbidity and …

[HTML][HTML] Cell-penetrating peptides (CPPs) as therapeutic and diagnostic agents for cancer

RA Bottens, T Yamada - Cancers, 2022 - mdpi.com
Simple Summary Crossing biological barriers is often required for drug delivery. Cell-
penetrating peptides (CPPs) are short strands of amino acids that have been widely used as …

ROS and p53: a versatile partnership

B Liu, Y Chen, DKS Clair - Free Radical Biology and Medicine, 2008 - Elsevier
The tumor suppressor protein p53 is a redox-active transcription factor that organizes and
directs cellular responses in the face of a variety of stresses that lead to genomic instability …

Diversity of the bacteriocins, their classification and potential applications in combat of antibiotic resistant and clinically relevant pathogens

GH Choi, WH Holzapfel, SD Todorov - Critical Reviews in …, 2023 - Taylor & Francis
There is almost a century since discovery of penicillin by Alexander Fleming, a century of
enthusiasm, abuse, facing development of antibiotic-resistance and clear conclusion that the …

Bacteriocins: perspective for the development of novel anticancer drugs

P Baindara, S Korpole, V Grover - Applied microbiology and biotechnology, 2018 - Springer
Antimicrobial peptides (AMPs) from prokaryotic source also known as bacteriocins are
ribosomally synthesized by bacteria belonging to different eubacterial taxonomic branches …

Mechanisms of angiogenesis in microbe-regulated inflammatory and neoplastic conditions

S Sajib, FT Zahra, MS Lionakis, NA German… - Angiogenesis, 2018 - Springer
Commensal microbiota inhabit all the mucosal surfaces of the human body. It plays
significant roles during homeostatic conditions, and perturbations in numbers and/or …