Cancer is one of the four major non‑communicable diseases (NCD), responsible for~ 14.6%
of all human deaths. Currently, there are> 100 different known types of cancer and> 500 …

We collated data from 157 unpublished cases of pediatric high-grade glioma and diffuse
intrinsic pontine glioma and 20 publicly available datasets in an integrated analysis of> …

Cancer cells are typically subject to profound metabolic alterations, including the Warburg
effect wherein cancer cells oxidize a decreased fraction of the pyruvate generated from …

Cancer differs significantly between men and women; even after adjusting for known
epidemiologic risk factors, the sexes differ in incidence, outcome, and response to therapy …

Cancer has been constantly evolving and so is the research pertaining to cancer diagnosis
and therapeutic regimens. Early detection and specific therapeutics are the key features of …

Monoclonal antibodies targeting the Epidermal Growth Factor Receptor (EGFR), such as
cetuximab and panitumumab, have evolved to important therapeutic options in metastatic …

Summary H3. 3G34R-mutant gliomas are lethal tumors of the cerebral hemispheres with
unknown mechanisms of regional specificity and tumorigenicity. We developed a human …

We present a meta-analysis of somatic copy number alterations (CNAs) from 11 publications
that examined 662 prostate cancer patient samples, which were derived from 546 primary …

Aims Mitochondrial dysfunction is a critical pathological change in cerebral ischemia.
Mitochondrial pyruvate carrier 1 (MPC1) is a mitochondrial inner membrane protein carrier …

Recurrent and clonal genetic alterations are characteristic of different subtypes of T-and B-
cell lymphoblastic leukemia (ALL), and several subtypes are strong independent predictors …