RNA-binding proteins and their role in the regulation of gene expression in Trypanosoma cruzi and Saccharomyces cerevisiae
RNA-binding proteins (RBPs) have important functions in the regulation of gene expression.
RBPs play key roles in post-transcriptional processes in all eukaryotes, such as splicing …
RBPs play key roles in post-transcriptional processes in all eukaryotes, such as splicing …
[HTML][HTML] RNA-binding proteins related to stress response and differentiation in protozoa
RNA-binding proteins (RBPs) are key regulators of gene expression. There are several
distinct families of RBPs and they are involved in the cellular response to environmental …
distinct families of RBPs and they are involved in the cellular response to environmental …
Comparative transcriptome profiling of virulent and non-virulent Trypanosoma cruzi underlines the role of surface proteins during infection
Trypanosoma cruzi, the protozoan that causes Chagas disease, has a complex life cycle
involving several morphologically and biochemically distinct stages that establish intricate …
involving several morphologically and biochemically distinct stages that establish intricate …
Trypanosoma cruzi Response to Sterol Biosynthesis Inhibitors: Morphophysiological Alterations Leading to Cell Death
The protozoan parasite Trypanosoma cruzi displays similarities to fungi in terms of its sterol
lipid biosynthesis, as ergosterol and other 24-alkylated sterols are its principal endogenous …
lipid biosynthesis, as ergosterol and other 24-alkylated sterols are its principal endogenous …
RNA-Seq reveals that overexpression of TcUBP1 switches the gene expression pattern toward that of the infective form of Trypanosoma cruzi
Trypanosomes regulate gene expression mainly by using posttranscriptional mechanisms.
Key factors responsible for carrying out this regulation are RNA-binding proteins, affecting …
Key factors responsible for carrying out this regulation are RNA-binding proteins, affecting …
RNA Binding Proteins and Gene Expression Regulation in Trypanosoma cruzi
The regulation of gene expression in trypanosomatids occurs mainly at the post-
transcriptional level. In the case of Trypanosoma cruzi, the characterization of messenger …
transcriptional level. In the case of Trypanosoma cruzi, the characterization of messenger …
Nuclear Compartmentalization Contributes to Stage-Specific Gene Expression Control in Trypanosoma cruzi
In the protozoan parasite Trypanosoma cruzi, as in other trypanosomatids, transcription of
protein coding genes occurs in a constitutive fashion, producing large polycistronic …
protein coding genes occurs in a constitutive fashion, producing large polycistronic …
Extensive translational regulation through the proliferative transition of Trypanosoma cruzi revealed by multi-omics
Trypanosoma cruzi is the etiological agent for Chagas disease, a neglected parasitic
disease in Latin America. Gene transcription control governs the eukaryotic cell replication …
disease in Latin America. Gene transcription control governs the eukaryotic cell replication …
[HTML][HTML] Genome-wide analysis of 3′-untranslated regions supports the existence of post-transcriptional regulons controlling gene expression in trypanosomes
In eukaryotic cells, a group of messenger ribonucleic acids (mRNAs) encoding functionally
interrelated proteins together with the trans-acting factors that coordinately modulate their …
interrelated proteins together with the trans-acting factors that coordinately modulate their …
The RNA-binding protein TcUBP1 up-regulates an RNA regulon for a cell surface–associated Trypanosoma cruzi glycoprotein and promotes parasite infectivity
KB Sabalette, MA Romaniuk, G Noé, A Cassola… - Journal of Biological …, 2019 - ASBMB
The regulation of transcription in trypanosomes is unusual. To modulate protein synthesis
during their complex developmental stages, these unicellular microorganisms rely largely on …
during their complex developmental stages, these unicellular microorganisms rely largely on …