Mitral valve disease—morphology and mechanisms
Mitral valve disease is a frequent cause of heart failure and death. Emerging evidence
indicates that the mitral valve is not a passive structure, but—even in adult life—remains …
indicates that the mitral valve is not a passive structure, but—even in adult life—remains …
Growing matter: a review of growth in living systems
E Kuhl - Journal of the Mechanical Behavior of Biomedical …, 2014 - Elsevier
Living systems can grow, develop, adapt, and evolve. These phenomena are non-intuitive to
traditional engineers and often difficult to understand. Yet, classical engineering tools can …
traditional engineers and often difficult to understand. Yet, classical engineering tools can …
Stress relaxation in epithelial monolayers is controlled by the actomyosin cortex
Epithelial monolayers are one-cell-thick tissue sheets that line most of the body surfaces,
separating internal and external environments. As part of their function, they must withstand …
separating internal and external environments. As part of their function, they must withstand …
Fully-coupled fluid-structure interaction simulation of the aortic and mitral valves in a realistic 3D left ventricle model
In this study, we present a fully-coupled fluid-structure interaction (FSI) framework that
combines smoothed particle hydrodynamics (SPH) and nonlinear finite element (FE) method …
combines smoothed particle hydrodynamics (SPH) and nonlinear finite element (FE) method …
Finite element modeling of mitral valve dynamic deformation using patient-specific multi-slices computed tomography scans
The objective of this study was to develop a patient-specific finite element (FE) model of a
human mitral valve. The geometry of the mitral valve was reconstructed from multi-slice …
human mitral valve. The geometry of the mitral valve was reconstructed from multi-slice …
Isogeometric Kirchhoff–Love shell formulations for biological membranes
Computational modeling of thin biological membranes can aid the design of better medical
devices. Remarkable biological membranes include skin, alveoli, blood vessels, and heart …
devices. Remarkable biological membranes include skin, alveoli, blood vessels, and heart …
Computational modeling of cardiac valve function and intervention
In the past two decades, major advances have been made in the clinical evaluation and
treatment of valvular heart disease owing to the advent of noninvasive cardiac imaging …
treatment of valvular heart disease owing to the advent of noninvasive cardiac imaging …
An inverse modeling approach for stress estimation in mitral valve anterior leaflet valvuloplasty for in-vivo valvular biomaterial assessment
Estimation of regional tissue stresses in the functioning heart valve remains an important
goal in our understanding of normal valve function and in develo** novel engineered …
goal in our understanding of normal valve function and in develo** novel engineered …
On the effect of prestrain and residual stress in thin biological membranes
Understanding the difference between ex vivo and in vivo measurements is critical to
interpret the load carrying mechanisms of living biological systems. For the past four …
interpret the load carrying mechanisms of living biological systems. For the past four …
On the In Vivo Deformation of the Mitral Valve Anterior Leaflet: Effects of Annular Geometry and Referential Configuration
Alteration of the native mitral valve (MV) shape has been hypothesized to have a profound
effect on the local tissue stress distribution, and is potentially linked to limitations in repair …
effect on the local tissue stress distribution, and is potentially linked to limitations in repair …