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[HTML][HTML] Molecular mechanisms of ferroptosis and their involvement in brain diseases
I Costa, DJ Barbosa, S Benfeito, V Silva… - Pharmacology & …, 2023 - Elsevier
Ferroptosis is a type of regulated cell death characterized by intracellular accumulation of
iron and reactive oxygen species, inhibition of system Xc-, glutathione depletion …
iron and reactive oxygen species, inhibition of system Xc-, glutathione depletion …
Targeting epigenetic and posttranslational modifications regulating ferroptosis for the treatment of diseases
Y Wang, J Hu, S Wu, JS Fleishman, Y Li, Y Xu… - Signal transduction and …, 2023 - nature.com
Ferroptosis, a unique modality of cell death with mechanistic and morphological differences
from other cell death modes, plays a pivotal role in regulating tumorigenesis and offers a …
from other cell death modes, plays a pivotal role in regulating tumorigenesis and offers a …
[HTML][HTML] Nrf2 regulates oxidative stress and its role in cerebral ischemic stroke
Cerebral ischemic stroke is characterized by acute ischemia in a certain part of the brain,
which leads to brain cells necrosis, apoptosis, ferroptosis, pyroptosis, etc. At present, there …
which leads to brain cells necrosis, apoptosis, ferroptosis, pyroptosis, etc. At present, there …
[HTML][HTML] Ferroptosis in Parkinson's disease: glia–neuron crosstalk
ZL Wang, L Yuan, W Li, JY Li - Trends in molecular medicine, 2022 - cell.com
Parkinson's disease (PD) is characterized by dopaminergic (DA) neuron loss and the
formation of cytoplasmic protein inclusions. Although the exact pathogenesis of PD is …
formation of cytoplasmic protein inclusions. Although the exact pathogenesis of PD is …
Pharmacological inhibition of ferroptosis as a therapeutic target for neurodegenerative diseases and strokes
Y Wang, S Wu, Q Li, H Sun, H Wang - Advanced Science, 2023 - Wiley Online Library
Emerging evidence suggests that ferroptosis, a unique regulated cell death modality that is
morphologically and mechanistically different from other forms of cell death, plays a vital role …
morphologically and mechanistically different from other forms of cell death, plays a vital role …
Ferroptosis in Parkinson's disease: molecular mechanisms and therapeutic potential
X Ding, L Gao, Z Han, S Eleuteri, W Shi, Y Shen… - Ageing research …, 2023 - Elsevier
Parkinson's Disease (PD) is characterized by the progressive loss of dopaminergic neurons
in the substantia nigra (SN), leading to motor and non-motor symptoms. While the exact …
in the substantia nigra (SN), leading to motor and non-motor symptoms. While the exact …
Ferroptosis mechanisms involved in neurodegenerative diseases
Ferroptosis is a type of cell death that was described less than a decade ago. It is caused by
the excess of free intracellular iron that leads to lipid (hydro) peroxidation. Iron is essential …
the excess of free intracellular iron that leads to lipid (hydro) peroxidation. Iron is essential …
The emerging roles of MAPK-AMPK in ferroptosis regulatory network
X Wang, X Tan, J Zhang, J Wu, H Shi - Cell Communication and Signaling, 2023 - Springer
Ferroptosis, a newform of programmed cell death, driven by peroxidative damages of
polyunsaturated-fatty-acid-containing phospholipids in cellular membranes and is extremely …
polyunsaturated-fatty-acid-containing phospholipids in cellular membranes and is extremely …
Dimethyl fumarate improves cognitive deficits in chronic cerebral hypoperfusion rats by alleviating inflammation, oxidative stress, and ferroptosis via NRF2/ARE/NF-κB …
N Yan, Z Xu, C Qu, JJ Zhang - International Immunopharmacology, 2021 - Elsevier
Cerebrovascular disease and its risk factors cause persistent decrease of cerebral blood
flow, chronic cerebral hypoperfusion (CCH) is the major foundation of vascular cognitive …
flow, chronic cerebral hypoperfusion (CCH) is the major foundation of vascular cognitive …
Baicalein limits osteoarthritis development by inhibiting chondrocyte ferroptosis
Y Wan, H Yu, W Fan - Free Radical Biology and Medicine, 2023 - Elsevier
Osteoarthritis (OA) is a common degenerative disease of articular cartilage, and there is
currently no effective treatment. Baicalein, a flavonoid extracted from plants of the Scutellaria …
currently no effective treatment. Baicalein, a flavonoid extracted from plants of the Scutellaria …