Painful and non-painful diabetic neuropathy, diagnostic challenges and implications for future management

TS Jensen, P Karlsson, SS Gylfadottir, ST Andersen… - Brain, 2021 - academic.oup.com
Peripheral neuropathy is one of the most common complications of both type 1 and type 2
diabetes. Up to half of patients with diabetes develop neuropathy during the course of their …

New insights into the mechanisms of diabetic complications: role of lipids and lipid metabolism

S Eid, KM Sas, SF Abcouwer, EL Feldman, TW Gardner… - Diabetologia, 2019 - Springer
Diabetes adversely affects multiple organs, including the kidney, eye and nerve, leading to
diabetic kidney disease, diabetic retinopathy and diabetic neuropathy, respectively. In both …

The role of neurotropic B vitamins in nerve regeneration

S Baltrusch - BioMed research international, 2021 - Wiley Online Library
Damage and regeneration naturally occur in the peripheral nervous system. The neurotropic
B vitamins thiamine (B1), pyridoxine (B6), and cobalamin (B12) are key players, which …

The effectiveness of topical cannabidiol oil in symptomatic relief of peripheral neuropathy of the lower extremities

DH Xu, BD Cullen, M Tang… - Current pharmaceutical …, 2020 - benthamdirect.com
Background: Peripheral neuropathy can significantly impact the quality of life for those who
are affected, as therapies from the current treatment algorithm often fail to deliver adequate …

The diagnostic challenge of small fibre neuropathy: clinical presentations, evaluations, and causes

AJ Terkelsen, P Karlsson, G Lauria, R Freeman… - The lancet …, 2017 - thelancet.com
Small fibre neuropathies are a heterogeneous group of disorders affecting thinly myelinated
Aδ-fibres and unmyelinated C-fibres. Although multiple causes of small nerve fibre …

Peripheral neuropathy: evaluation and differential diagnosis

G Castelli, KM Desai, RE Cantone - American family physician, 2020 - aafp.org
Peripheral neuropathy, a common neurologic problem encountered by family physicians,
can be classified clinically by the anatomic pattern of presenting symptoms and, if indicated …

Diagnosis of peripheral neuropathy

HC Lehmann, G Wunderlich, GR Fink… - Neurological research and …, 2020 - Springer
Introduction Peripheral neuropathy represents a spectrum of diseases with different
etiologies. The most common causes are diabetes, exposure to toxic substances including …

Diabetic neuropathy

EL Feldman, BC Callaghan, R Pop-Busui… - Nature reviews Disease …, 2019 - nature.com
The global epidemic of prediabetes and diabetes has led to a corresponding epidemic of
complications of these disorders. The most prevalent complication is neuropathy, of which …

Diabetic neuropathy: what does the future hold?

BC Callaghan, G Gallagher, V Fridman, EL Feldman - Diabetologia, 2020 - Springer
Frustratingly, disease-modifying treatments for diabetic neuropathy remain elusive.
Glycaemic control has a robust effect on preventing neuropathy in individuals with type 1 but …

Diabetes and obesity are the main metabolic drivers of peripheral neuropathy

BC Callaghan, LL Gao, Y Li, X Zhou… - Annals of clinical …, 2018 - Wiley Online Library
Objective To determine the associations between individual metabolic syndrome (MetS)
components and peripheral neuropathy in a large population‐based cohort from **gu …