MALDI-TOF mass spectrometry in clinical analysis and research

D Li, J Yi, G Han, L Qiao - ACS measurement science au, 2022 - ACS Publications
In the decade after being awarded the Nobel Prize in Chemistry in 2002, matrix-assisted
laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS) has been …

[HTML][HTML] Advances in capillary electrophoresis for the life sciences

JS Torano, R Ramautar, G de Jong - Journal of Chromatography B, 2019 - Elsevier
Capillary electrophoresis (CE) played an important role in developments in the life sciences.
The technique is nowadays used for the analysis of both large and small molecules in …

High capacity capillary electrophoresis-electrospray ionization mass spectrometry: coupling a porous sheathless interface with transient-isotachophoresis

JM Busnel, B Schoenmaker, R Ramautar… - Analytical …, 2010 - ACS Publications
A sheathless interface making use of a porous tip has been used for coupling capillary
electrophoresis and electrospray ionization mass spectrometry. First, effective flow rates …

Interfacing droplet microfluidics with matrix-assisted laser desorption/ionization mass spectrometry: label-free content analysis of single droplets

SK Küster, SR Fagerer, PE Verboket, K Eyer… - Analytical …, 2013 - ACS Publications
Droplet-based microfluidic systems have become a very powerful tool to miniaturize
chemical and biological reactions. However, droplet content analysis remains challenging …

Insights from capillary electrophoresis approaches for characterization of monoclonal antibodies and antibody drug conjugates in the period 2016–2018

A Lechner, J Giorgetti, R Gahoual, A Beck… - … of Chromatography B, 2019 - Elsevier
Monoclonal antibodies (mAbs) and their related products as antibody-drug-conjugates
(ADCs) or biosimilars represent a constantly growing class of molecules therapeutic proteins …

Ultra-low flow electrospray ionization-mass spectrometry for improved ionization efficiency in phosphoproteomics

AAM Heemskerk, JM Busnel, B Schoenmaker… - Analytical …, 2012 - ACS Publications
The potential benefits of ultra-low flow electrospray ionization (ESI) for the analysis of
phosphopeptides in proteomics was investigated. First, the relative flow dependent …

Coupling of CE‐MS for protein and peptide analysis

I Mikšík - Journal of separation science, 2019 - Wiley Online Library
The review is focused on the latest developments in the analysis of proteins and peptides by
capillary electrophoresis techniques coupled to mass spectrometry. First, the methodology …

CE‐MS‐based proteomics in biomarker discovery and clinical application

C Pontillo, S Filip, DM Borràs, W Mullen… - PROTEOMICS …, 2015 - Wiley Online Library
CE‐MS is applied in clinical proteomics for both the identification of biomarkers of disease
and assessment of biomarkers in clinical diagnosis. The analysis is reproducible, fast, and …

Capillary electromigration techniques coupled to mass spectrometry: Applications to food analysis

DP Vijay, SA Shamsi, K Sutherland - TrAC Trends in Analytical Chemistry, 2021 - Elsevier
Abstract Analysis of food is essential for safety, quality control, government regulations, and
recommendations to answer basic research questions. Capillary electrophoresis-mass …

CE–MS for proteomics: Advances in interface development and application

R Ramautar, AAM Heemskerk, PJ Hensbergen… - Journal of …, 2012 - Elsevier
Capillary electrophoresis–mass spectrometry (CE–MS) has emerged as a powerful
technique for the analysis of proteins and peptides. Over the past few years, significant …